Cytodiagnosis of in situ and early carcinoma of the upper gastrointestinal tract

Lydia P Howell, A. L. Wright, S. A. Calafati, S. Rosen, I. Koprowska

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Three cases of adenocarcinoma of the stomach, two in situ and one superficially invasive, and one of superficially invasive squamous-cell carcinoma of the esophagus are presented to illustrate the problems encountered in the diagnosis of early lesions of the upper gastrointestinal (GI) tract and the contribution that cytodiagnosis can make. The symptomalogy and roentgenographic findings in these cases were largely nonspecific. While endoscopic biopsies were repeatedly negative in three of the four cases, endoscopic brushing cytology consistently indicated the presence of a malignancy. Surgery was finally performed on the basis of the cytologic findings, confirming the presence of early malignancy. The cytologic findings, with histologic correlations, are presented in an effort to define some specific criteria for the diagnosis of early malignancy of the upper GI tract.

Original languageEnglish (US)
Pages (from-to)269-273
Number of pages5
JournalActa Cytologica
Issue number3
StatePublished - 1985
Externally publishedYes

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology


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