Cystic Fibrosis in Adults: Current and Future Management Strategies

Brian M Morrissey, Bettina C. Schock, Gregory P. Marelich, Carroll E Cross

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Over 30,000 individuals in the United States of America are living with cystic fibrosis (CF). Despite incremental advances in care and understanding of its pathophysiology, CF remains a significantly life-limiting disease. Readily accessible newborn screening, genetic testing, and an improved awareness have increased the early recognition of CF, atypical presentations of CF, and the CF-related diseases. Improvements in medical management have led to continually improving life expectancy for patients with CF. Despite improved management strategies, severe lung disease remains the commonly life-limiting pathology. We review the pathophysiology, diagnosis, and management of the respiratory-tract manifestations of CF that represent the life-limiting aspects of the condition and summarize upcoming and possible future therapies for patients with CF.

Original languageEnglish (US)
Pages (from-to)275-287
Number of pages13
JournalClinical Reviews in Allergy and Immunology
Issue number3
StatePublished - Dec 2003


  • Adult
  • CF
  • CFTR
  • Cystic fibrosis

ASJC Scopus subject areas

  • Immunology and Allergy


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