Abstract
An intramolecular Lewis acid-promoted conjugate addition of a propargylic silane to a functionalized cyclohex-2-en-1-one resulted in part in the remarkable formation of a highly fused cyclobutene. The reaction was found to be dependent on the stoichiometry and selection of Lewis acid.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 5499-5502 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 36 |
| Issue number | 31 |
| DOIs | |
| State | Published - Jul 31 1995 |
ASJC Scopus subject areas
- Biochemistry
- Organic Chemistry
- Drug Discovery
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Cite this
Spence, J. D., Lowrie, L. E., & Nantz, M. H. (1995). Cyclobutene formation accompanying an intramolecular Lewis acid-promoted spirocyclization of a propargylic silane. Tetrahedron Letters, 36(31), 5499-5502. https://doi.org/10.1016/0040-4039(95)01115-X