Abstract
Invasive fungal infections are increasing in incidence, along with the use of immunosuppressive medications for the prevention of organ transplant rejection, graft versus host disease and treatment of auto-immune disorders. Additionally, the incidence of invasive fungal infections is increasing with the use of new antineoplastic therapies for malignancy, increasing incidence of diabetes mellitus, expanded use of broad-spectrum antimicrobial therapy and with an aging population with chronic medical problems such as chronic renal failure, chronic obstructive pulmonary disease and HIV. We present a case of primary cutaneous zygomycosis at the insertion site of a central venous catheter in a 45-year-old renal transplant patient admitted for acute pancreatitis. In the critical care setting, clinicians must retain a high index of suspicion for invasive fungal infections in immunocompromised individuals to ensure early diagnosis and provide aggressive medical and surgical intervention. Liposomal amphoterin B is the first line antimicrobial therapy, and reduction or discontinuation of immunosuppressive therapy should be considered. Currently there are no consensus opinions or recommendations for routine, scheduled replacement of central venous catheters to prevent infections, even in immunosuppressed patients.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 83-86 |
| Number of pages | 4 |
| Journal | Healthcare Infection |
| Volume | 17 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 2012 |
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ASJC Scopus subject areas
- Infectious Diseases
Cite this
Cutaneous Rhizopus infection at a central venous catheter site in a critically ill renal transplant patient. / Quinez, Zoel A.; Speicher, John T.; Sebat, Christian; Avdalovic, Mark V.
In: Healthcare Infection, Vol. 17, No. 3, 09.2012, p. 83-86.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Cutaneous Rhizopus infection at a central venous catheter site in a critically ill renal transplant patient
AU - Quinez, Zoel A.
AU - Speicher, John T.
AU - Sebat, Christian
AU - Avdalovic, Mark V
PY - 2012/9
Y1 - 2012/9
N2 - Invasive fungal infections are increasing in incidence, along with the use of immunosuppressive medications for the prevention of organ transplant rejection, graft versus host disease and treatment of auto-immune disorders. Additionally, the incidence of invasive fungal infections is increasing with the use of new antineoplastic therapies for malignancy, increasing incidence of diabetes mellitus, expanded use of broad-spectrum antimicrobial therapy and with an aging population with chronic medical problems such as chronic renal failure, chronic obstructive pulmonary disease and HIV. We present a case of primary cutaneous zygomycosis at the insertion site of a central venous catheter in a 45-year-old renal transplant patient admitted for acute pancreatitis. In the critical care setting, clinicians must retain a high index of suspicion for invasive fungal infections in immunocompromised individuals to ensure early diagnosis and provide aggressive medical and surgical intervention. Liposomal amphoterin B is the first line antimicrobial therapy, and reduction or discontinuation of immunosuppressive therapy should be considered. Currently there are no consensus opinions or recommendations for routine, scheduled replacement of central venous catheters to prevent infections, even in immunosuppressed patients.
AB - Invasive fungal infections are increasing in incidence, along with the use of immunosuppressive medications for the prevention of organ transplant rejection, graft versus host disease and treatment of auto-immune disorders. Additionally, the incidence of invasive fungal infections is increasing with the use of new antineoplastic therapies for malignancy, increasing incidence of diabetes mellitus, expanded use of broad-spectrum antimicrobial therapy and with an aging population with chronic medical problems such as chronic renal failure, chronic obstructive pulmonary disease and HIV. We present a case of primary cutaneous zygomycosis at the insertion site of a central venous catheter in a 45-year-old renal transplant patient admitted for acute pancreatitis. In the critical care setting, clinicians must retain a high index of suspicion for invasive fungal infections in immunocompromised individuals to ensure early diagnosis and provide aggressive medical and surgical intervention. Liposomal amphoterin B is the first line antimicrobial therapy, and reduction or discontinuation of immunosuppressive therapy should be considered. Currently there are no consensus opinions or recommendations for routine, scheduled replacement of central venous catheters to prevent infections, even in immunosuppressed patients.
UR - http://www.scopus.com/inward/record.url?scp=84865856661&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84865856661&partnerID=8YFLogxK
U2 - 10.1071/HI12011
DO - 10.1071/HI12011
M3 - Article
AN - SCOPUS:84865856661
VL - 17
SP - 83
EP - 86
JO - Infection, Disease and Health
JF - Infection, Disease and Health
SN - 2468-0451
IS - 3
ER -