Abstract
Artificial transcription factors based on modified zinc-finger DNA-binding domains have been shown to activate or repress the transcription of endogenous genes in multiple organisms. Advances in both the construction of novel zinc-finger proteins and our understanding of the characteristics of a productive regulatory site have fueled these achievements.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 632-637 |
| Number of pages | 6 |
| Journal | Current Opinion in Biotechnology |
| Volume | 12 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 1 2001 |
| Externally published | Yes |
ASJC Scopus subject areas
- Biotechnology
Fingerprint Dive into the research topics of 'Custom DNA-binding proteins come of age: Polydactyl zinc-finger proteins'. Together they form a unique fingerprint.
Cite this
Segal, D., & Barbas, C. F. (2001). Custom DNA-binding proteins come of age: Polydactyl zinc-finger proteins. Current Opinion in Biotechnology, 12(6), 632-637. https://doi.org/10.1016/S0958-1669(01)00272-5