Abstract
Artificial transcription factors based on modified zinc-finger DNA-binding domains have been shown to activate or repress the transcription of endogenous genes in multiple organisms. Advances in both the construction of novel zinc-finger proteins and our understanding of the characteristics of a productive regulatory site have fueled these achievements.
Original language | English (US) |
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Pages (from-to) | 632-637 |
Number of pages | 6 |
Journal | Current Opinion in Biotechnology |
Volume | 12 |
Issue number | 6 |
DOIs | |
State | Published - Dec 1 2001 |
Externally published | Yes |
ASJC Scopus subject areas
- Biotechnology