Current surgical management of infected pancreatic necrosis

Brendan Boland, Steven D Colquhoun, Vijay Menon, Amanda Kim, Simon Lo, Nicholas N. Nissen

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Infected pancreatic necrosis (IPN) continues to be a challenging problem for the surgeon. We reviewed the experience on a hepatobiliary surgical service with patients who required operative intervention for IPN with emphasis on surgical approach, timing of surgery, and complications. Between 2002 and 2008, 21 patients underwent surgery for IPN. The initial surgical approach in these 21 patients included either direct pancreatic débridement (DPD, n = 13) or transgastric débridement using cyst-gastrostomy (CG, n = 8). Fifteen patients (71%) required only a single procedure, whereas three (14%) required two procedures and three (14%) required three procedures. The mean time from onset of pancreatitis to operation was 77 days. Patients requiring a single intervention had a longer interval from onset of pancreatitis to surgery compared with those requiring multiple interventions. When comparing CG and DPD groups, there was a longer interval from onset of pancreatitis to débridement, a lower chance of needing multiple débridements, and fewer pancreatic fistulae in the CG group. Overall survival was 95 per cent. Our results demonstrate that CG can be successfully used in select patients with IPN. Patients undergoing CG are less likely to require repeat surgical débridement and to develop pancreatic fistulae compared with patients undergoing DPD.

Original languageEnglish (US)
Pages (from-to)1096-1099
Number of pages4
JournalAmerican Surgeon
Issue number10
StatePublished - Oct 1 2010
Externally publishedYes

ASJC Scopus subject areas

  • Surgery


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