CT Volumetry and Basic Texture Analysis as Surrogate Markers in Advanced Non–small-cell Lung Cancer

Benjamin Owen, David Gandara, Karen Kelly, Elizabeth Moore, David Shelton, Friedrich Knollmann

Research output: Contribution to journalArticlepeer-review

Abstract

We performed a retrospective study comparing volumetric and unidimensional tumor size measurements in patients with advanced non–small-cell lung cancer. Cox regression analysis of the 77 patients analyzed demonstrated that only change in tumor volume and the initial tumor size predicted survival, indicating that volume is a better marker of survival compared with the diameter measurements that underlie Response Evaluation Criteria In Solid Tumors (RECIST).

Original languageEnglish (US)
JournalClinical lung cancer
DOIs
StateAccepted/In press - Jan 1 2019

Keywords

  • Chemotherapy
  • Diameter
  • High resolution
  • Response Evaluation Criteria in Solid Tumors
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

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