CT Volumetry and Basic Texture Analysis as Surrogate Markers in Advanced Non–small-cell Lung Cancer

Research output: Contribution to journalArticle

Abstract

We performed a retrospective study comparing volumetric and unidimensional tumor size measurements in patients with advanced non–small-cell lung cancer. Cox regression analysis of the 77 patients analyzed demonstrated that only change in tumor volume and the initial tumor size predicted survival, indicating that volume is a better marker of survival compared with the diameter measurements that underlie Response Evaluation Criteria In Solid Tumors (RECIST).

Original languageEnglish (US)
JournalClinical lung cancer
DOIs
StateAccepted/In press - Jan 1 2019

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Non-Small Cell Lung Carcinoma
Biomarkers
Survival
Tumor Burden
Neoplasms
Retrospective Studies
Regression Analysis
Response Evaluation Criteria in Solid Tumors

Keywords

  • Chemotherapy
  • Diameter
  • High resolution
  • Response Evaluation Criteria in Solid Tumors
  • Survival

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine
  • Cancer Research

Cite this

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abstract = "We performed a retrospective study comparing volumetric and unidimensional tumor size measurements in patients with advanced non–small-cell lung cancer. Cox regression analysis of the 77 patients analyzed demonstrated that only change in tumor volume and the initial tumor size predicted survival, indicating that volume is a better marker of survival compared with the diameter measurements that underlie Response Evaluation Criteria In Solid Tumors (RECIST).",
keywords = "Chemotherapy, Diameter, High resolution, Response Evaluation Criteria in Solid Tumors, Survival",
author = "Benjamin Owen and David Gandara and Karen Kelly and Elizabeth Moore and David Shelton and Friedrich Knollmann",
year = "2019",
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language = "English (US)",
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AU - Knollmann, Friedrich

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KW - Response Evaluation Criteria in Solid Tumors

KW - Survival

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