Cross-protection studies between feline infectious peritonitis and porcine transmissible gastroenteritis viruses

R. D. Woods, Niels C Pedersen

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Cross-protection studies between the feline infectious peritonitis (FIP) and the porcine transmissible gastroenteritis (TGE) viruses were conducted in cats, pigs and pregnant gilts. Cats vaccinated with TGE virus developed neutralizing antibodies against TGE virus and low titer antibody against FIP virus detected by an indirect fluorescent antibody technique but were not protected against a virulent FIP virus challenge. Baby pigs and pregnant gilts vaccinated with FIP virus did not develop detectable antibodies to TGE virus. Nevertheless, it appeared that vaccination of swine with FIP virus conferred some immunity against TGE virus infection. Seventeen-day-old pigs vaccinated with two doses of FIP virus had a 67% survival rate following a virulent TGE virus challenge, and 75% of the 3-day-old pigs suckling either FIP or TGE-virus-vaccinated gilts survived virulent TGE virus infection in contrast to 0% survival of baby pigs suckling unvaccinated gilts.

Original languageEnglish (US)
Pages (from-to)11-16
Number of pages6
JournalVeterinary Microbiology
Volume4
Issue number1
DOIs
StatePublished - 1979

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Feline Infectious Peritonitis
Transmissible gastroenteritis virus
Cross Protection
feline infectious peritonitis
Feline Coronavirus
Feline coronavirus
Swine
gilts
swine
Virus Diseases
suckling
piglets
Cats
cats
antibodies
Antibodies
Indirect Fluorescent Antibody Technique
Neutralizing Antibodies
Viral Load
neutralizing antibodies

ASJC Scopus subject areas

  • Animal Science and Zoology
  • Microbiology
  • veterinary(all)

Cite this

Cross-protection studies between feline infectious peritonitis and porcine transmissible gastroenteritis viruses. / Woods, R. D.; Pedersen, Niels C.

In: Veterinary Microbiology, Vol. 4, No. 1, 1979, p. 11-16.

Research output: Contribution to journalArticle

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