Critical illness-related corticosteroid insufficiency in a dog with septic shock: Case Report

Jamie L. Peyton, Jamie Burkitt Creedon

Research output: Contribution to journalArticle

23 Scopus citations


Objective To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.

Original languageEnglish (US)
Pages (from-to)262-268
Number of pages7
JournalJournal of Veterinary Emergency and Critical Care
Issue number3
StatePublished - Jun 1 2009



  • Aspiration pneumonia
  • Critical care
  • Endocrinology
  • Hypotension
  • Systemic inflammatory response syndrome

ASJC Scopus subject areas

  • veterinary(all)

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