Abstract
Objective To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 262-268 |
| Number of pages | 7 |
| Journal | Journal of Veterinary Emergency and Critical Care |
| Volume | 19 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jun 1 2009 |
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Keywords
- Aspiration pneumonia
- Critical care
- Endocrinology
- Hypotension
- Systemic inflammatory response syndrome
ASJC Scopus subject areas
- veterinary(all)
Cite this
Critical illness-related corticosteroid insufficiency in a dog with septic shock : Case Report. / Peyton, Jamie L.; Burkitt Creedon, Jamie.
In: Journal of Veterinary Emergency and Critical Care, Vol. 19, No. 3, 01.06.2009, p. 262-268.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Critical illness-related corticosteroid insufficiency in a dog with septic shock
T2 - Case Report
AU - Peyton, Jamie L.
AU - Burkitt Creedon, Jamie
PY - 2009/6/1
Y1 - 2009/6/1
N2 - Objective To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.
AB - Objective To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.
KW - Aspiration pneumonia
KW - Critical care
KW - Endocrinology
KW - Hypotension
KW - Systemic inflammatory response syndrome
UR - http://www.scopus.com/inward/record.url?scp=67049136113&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67049136113&partnerID=8YFLogxK
U2 - 10.1111/j.1476-4431.2009.00407.x
DO - 10.1111/j.1476-4431.2009.00407.x
M3 - Article
VL - 19
SP - 262
EP - 268
JO - Journal of Veterinary Emergency and Critical Care
JF - Journal of Veterinary Emergency and Critical Care
SN - 1479-3261
IS - 3
ER -