Critical illness-related corticosteroid insufficiency in a dog with septic shock

Case Report

Jamie L. Peyton, Jamie Burkitt Creedon

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

Objective To describe a case of hydrocortisone-responsive hypotension and critical illness-related corticosteroid insufficiency (CIRCI) in a dog with septic shock. Case Summary A dog with aspiration pneumonia developed septic shock with pressor-refractory hypotension. A standard ACTH stimulation test was performed that showed a blunted cortisol response consistent with CIRCI. Reversal of shock was achieved within 2 hours of hydrocortisone administration, and complete weaning from pressors was accomplished over the subsequent 8 hours. The patient recovered and was discharged from the hospital. An ACTH stimulation test performed 1 month after hospital discharge showed normal adrenal responsiveness consistent with resolution of CIRCI. New or Unique Information Provided This case is the first published report of hydrocortisone-responsive hypotension and transient CIRCI associated with naturally occurring septic shock in a dog.

Original languageEnglish (US)
Pages (from-to)262-268
Number of pages7
JournalJournal of Veterinary Emergency and Critical Care
Volume19
Issue number3
DOIs
StatePublished - Jun 1 2009

Fingerprint

septic shock
adrenal cortex hormones
Septic Shock
Critical Illness
cortisol
Hydrocortisone
hypotension
Adrenal Cortex Hormones
Dogs
Hypotension
case studies
dogs
corticotropin
Adrenocorticotropic Hormone
Aspiration Pneumonia
Weaning
pneumonia
Shock
weaning
testing

Keywords

  • Aspiration pneumonia
  • Critical care
  • Endocrinology
  • Hypotension
  • Systemic inflammatory response syndrome

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Critical illness-related corticosteroid insufficiency in a dog with septic shock : Case Report. / Peyton, Jamie L.; Burkitt Creedon, Jamie.

In: Journal of Veterinary Emergency and Critical Care, Vol. 19, No. 3, 01.06.2009, p. 262-268.

Research output: Contribution to journalArticle

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