CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies

Channabasavaiah B. Gurumurthy, Rolen M. Quadros, Masahiro Sato, Tomoji Mashimo, Kevin C K Lloyd, Masato Ohtsuka

Research output: Chapter in Book/Report/Conference proceedingChapter

4 Citations (Scopus)

Abstract

The CRISPR revolution that began in 2013 has been adopted and embraced by many researchers worldwide, including the mouse molecular genetics community. CRISPR represents one of only a few radical and transformative shifts in transgenic technologies over the past 30 years. This chapter discusses the paradigm shift that CRISPR technology has brought about in the field of mouse genome editing.

Original languageEnglish (US)
Title of host publicationGenome Editing
PublisherSpringer International Publishing
Pages65-77
Number of pages13
ISBN (Electronic)9783319341484
ISBN (Print)9783319341460
DOIs
StatePublished - Jan 1 2016

Fingerprint

Clustered Regularly Interspaced Short Palindromic Repeats
Genes
Genome
Technology
genome
mice
molecular genetics
researchers
genetically modified organisms
Molecular Biology
Research Personnel

Keywords

  • CRISPR/Cas9
  • Genome editing
  • Knock-in
  • Knockout
  • Microinjection
  • Mouse genome
  • Transgenic

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

Cite this

Gurumurthy, C. B., Quadros, R. M., Sato, M., Mashimo, T., Lloyd, K. C. K., & Ohtsuka, M. (2016). CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. In Genome Editing (pp. 65-77). Springer International Publishing. https://doi.org/10.1007/978-3-319-34148-4_4

CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. / Gurumurthy, Channabasavaiah B.; Quadros, Rolen M.; Sato, Masahiro; Mashimo, Tomoji; Lloyd, Kevin C K; Ohtsuka, Masato.

Genome Editing. Springer International Publishing, 2016. p. 65-77.

Research output: Chapter in Book/Report/Conference proceedingChapter

Gurumurthy, CB, Quadros, RM, Sato, M, Mashimo, T, Lloyd, KCK & Ohtsuka, M 2016, CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. in Genome Editing. Springer International Publishing, pp. 65-77. https://doi.org/10.1007/978-3-319-34148-4_4
Gurumurthy CB, Quadros RM, Sato M, Mashimo T, Lloyd KCK, Ohtsuka M. CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. In Genome Editing. Springer International Publishing. 2016. p. 65-77 https://doi.org/10.1007/978-3-319-34148-4_4
Gurumurthy, Channabasavaiah B. ; Quadros, Rolen M. ; Sato, Masahiro ; Mashimo, Tomoji ; Lloyd, Kevin C K ; Ohtsuka, Masato. / CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies. Genome Editing. Springer International Publishing, 2016. pp. 65-77
@inbook{05dec60211b74060ab58b7fa0b20ea49,
title = "CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies",
abstract = "The CRISPR revolution that began in 2013 has been adopted and embraced by many researchers worldwide, including the mouse molecular genetics community. CRISPR represents one of only a few radical and transformative shifts in transgenic technologies over the past 30 years. This chapter discusses the paradigm shift that CRISPR technology has brought about in the field of mouse genome editing.",
keywords = "CRISPR/Cas9, Genome editing, Knock-in, Knockout, Microinjection, Mouse genome, Transgenic",
author = "Gurumurthy, {Channabasavaiah B.} and Quadros, {Rolen M.} and Masahiro Sato and Tomoji Mashimo and Lloyd, {Kevin C K} and Masato Ohtsuka",
year = "2016",
month = "1",
day = "1",
doi = "10.1007/978-3-319-34148-4_4",
language = "English (US)",
isbn = "9783319341460",
pages = "65--77",
booktitle = "Genome Editing",
publisher = "Springer International Publishing",

}

TY - CHAP

T1 - CRISPR/Cas9 and the paradigm shift in mouse genome manipulation technologies

AU - Gurumurthy, Channabasavaiah B.

AU - Quadros, Rolen M.

AU - Sato, Masahiro

AU - Mashimo, Tomoji

AU - Lloyd, Kevin C K

AU - Ohtsuka, Masato

PY - 2016/1/1

Y1 - 2016/1/1

N2 - The CRISPR revolution that began in 2013 has been adopted and embraced by many researchers worldwide, including the mouse molecular genetics community. CRISPR represents one of only a few radical and transformative shifts in transgenic technologies over the past 30 years. This chapter discusses the paradigm shift that CRISPR technology has brought about in the field of mouse genome editing.

AB - The CRISPR revolution that began in 2013 has been adopted and embraced by many researchers worldwide, including the mouse molecular genetics community. CRISPR represents one of only a few radical and transformative shifts in transgenic technologies over the past 30 years. This chapter discusses the paradigm shift that CRISPR technology has brought about in the field of mouse genome editing.

KW - CRISPR/Cas9

KW - Genome editing

KW - Knock-in

KW - Knockout

KW - Microinjection

KW - Mouse genome

KW - Transgenic

UR - http://www.scopus.com/inward/record.url?scp=85006414954&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85006414954&partnerID=8YFLogxK

U2 - 10.1007/978-3-319-34148-4_4

DO - 10.1007/978-3-319-34148-4_4

M3 - Chapter

AN - SCOPUS:85006414954

SN - 9783319341460

SP - 65

EP - 77

BT - Genome Editing

PB - Springer International Publishing

ER -