TY - JOUR
T1 - Creation of an NCI comparative brain tumor consortium
T2 - Informing the translation of new knowledge from canine to human brain tumor patients
AU - Leblanc, Amy K.
AU - Mazcko, Christina
AU - Brown, Diane E.
AU - Koehler, Jennifer W.
AU - Miller, Andrew D.
AU - Miller, C. Ryan
AU - Bentley, R. Timothy
AU - Packer, Rebecca A.
AU - Breen, Matthew
AU - Boudreau, C. Elizabeth
AU - Levine, Jonathan M.
AU - Simpson, R. Mark
AU - Halsey, Charles
AU - Kisseberth, William
AU - Rossmeisl, John H.
AU - Dickinson, Peter J
AU - Fan, Timothy M.
AU - Corps, Kara
AU - Aldape, Kenneth
AU - Puduvalli, Vinay
AU - Pluhar, G. Elizabeth
AU - Gilbert, Mark R.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - On September 14-15, 2015, a meeting of clinicians and investigators in the fields of veterinary and human neuro-oncology, clinical trials, neuropathology, and drug development was convened at the National Institutes of Health campus in Bethesda, Maryland. This meeting served as the inaugural event launching a new consortium focused on improving the knowledge, development of, and access to naturally occurring canine brain cancer, specifically glioma, as a model for human disease. Within the meeting, a SWOT (strengths, weaknesses, opportunities, and threats) assessment was undertaken to critically evaluate the role that naturally occurring canine brain tumors could have in advancing this aspect of comparative oncology aimed at improving outcomes for dogs and human beings. A summary of this meeting and subsequent discussion are provided to inform the scientific and clinical community of the potential for this initiative. Canine and human comparisons represent an unprecedented opportunity to complement conventional brain tumor research paradigms, addressing a devastating disease for which innovative diagnostic and treatment strategies are clearly needed.
AB - On September 14-15, 2015, a meeting of clinicians and investigators in the fields of veterinary and human neuro-oncology, clinical trials, neuropathology, and drug development was convened at the National Institutes of Health campus in Bethesda, Maryland. This meeting served as the inaugural event launching a new consortium focused on improving the knowledge, development of, and access to naturally occurring canine brain cancer, specifically glioma, as a model for human disease. Within the meeting, a SWOT (strengths, weaknesses, opportunities, and threats) assessment was undertaken to critically evaluate the role that naturally occurring canine brain tumors could have in advancing this aspect of comparative oncology aimed at improving outcomes for dogs and human beings. A summary of this meeting and subsequent discussion are provided to inform the scientific and clinical community of the potential for this initiative. Canine and human comparisons represent an unprecedented opportunity to complement conventional brain tumor research paradigms, addressing a devastating disease for which innovative diagnostic and treatment strategies are clearly needed.
KW - comparative oncology
KW - glioma
KW - translational research
UR - http://www.scopus.com/inward/record.url?scp=84985994793&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84985994793&partnerID=8YFLogxK
U2 - 10.1093/neuonc/now051
DO - 10.1093/neuonc/now051
M3 - Review article
C2 - 27179361
AN - SCOPUS:84985994793
VL - 18
SP - 1209
EP - 1218
JO - Neuro-Oncology
JF - Neuro-Oncology
SN - 1522-8517
IS - 9
ER -