Craniopharyngiomas - the utility of contrast medium enhancement for MR imaging at 1.5 T

J. K. Hald, O. P. Eldevik, James A Brunberg, W. F. Chandler

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


To evaluate the efficacy of i.v. contrast medium administration in MR imaging at 1.5 T in patients with craniopharyngiomas, MR studies of 10 men and 6 women with pathologically proven craniopharyngiomas were made. The MR images were obtained as 3- to 5-mm-thick coronal (n = 13) or axial (n = 3) T1-weighted images (T1WI) prior to and following i.v. Gd-DTPA administration. Proton density- (PD) and T2-weighted images (T2WI) were also obtained. Conspicuity of tumor margins, cystic versus solid components, size, location and effect upon adjacent structures were separately characterized in all imaging sequences. In 6 patients contrast medium-enhanced T1WI, PD and T2WI demonstrated cystic tumor components not seen on unenhanced T1WI. There were significant differences (p < 0.004) on 2-tailed Student's t-test comparing tumor conspicuity on contrast medium-enhanced T1WI with unenhanced T1WI, PD and T2WI. Optimal tumor delineation on MR imaging of patients with craniopharyngiomas justifies the use of i.v. contrast medium.

Original languageEnglish (US)
Pages (from-to)520-525
Number of pages6
JournalActa Radiologica
Issue number6
StatePublished - Nov 1994
Externally publishedYes

ASJC Scopus subject areas

  • Engineering(all)
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology


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