Corticotropin releasing factor (CRF) initiates a cascade of endocrine events collectively known as the neuroendocrine stress response. The CRF neuropeptide family includes the urocortins (Ucn1, Ucn2, and Ucn3). These neuropeptides signal via two CRF receptors and are subjected to the modulatory actions of several soluble binding-proteins. While CRF and urocortins are often associated with control of the stress response, they are also involved in arousal, anxiety, depression, feeding behavior, cardiovascular activity, pregnancy, and plasma glucose homeostasis.
|Original language||English (US)|
|Title of host publication||The Curated Reference Collection in Neuroscience and Biobehavioral Psychology|
|Publisher||Elsevier Science Ltd.|
|Number of pages||7|
|State||Published - Jan 1 2016|
- Cardiovascular system
ASJC Scopus subject areas