Corticosterone levels in mice exposed to high-intensity electric fields

Robert M. Hackman, H. B. Graves

Research output: Contribution to journalArticlepeer-review

26 Scopus citations


Plasma corticosterone concentration was determined by radioimmunoassay from mice exposed to 60 Hz electric fields from 0 to 50,000 V/m for durations ranging from 5 min to 6 weeks. Responses of mice exposed to known stressors such as handling, social mixing, and high-level noise were also assessed. An acute, transient increase in circulating corticosterone was apparent immediately after activation of a high-intensity electric field. The increase was apparent only for a matter of minutes, and corticosterone concentration after exposure of several hours, days, or weeks was normal. In contrast, mice which were moved, socially mixed, and exposed to high-level noise had corticosterone levels which were consistently two or three times greater than those of undisturbed mice or mice exposed to the high-intensity electric fields. Results were interpreted as meaning that mice may perceive high-intensity electric fields and exhibit orientation reactions to the onset of such fields.

Original languageEnglish (US)
Pages (from-to)201-213
Number of pages13
JournalBehavioral and Neural Biology
Issue number2
StatePublished - 1981
Externally publishedYes

ASJC Scopus subject areas

  • Physiology


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