Cortical temporal dynamics of visually guided behavior

Leighton B N Hinkley, Srikantan S. Nagarajan, Sarang S. Dalal, Adrian G. Guggisberg, Elizabeth A. Disbrow

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Little is known about the temporal dynamics of cortical activation during visually guided behavior. We measured changes in brain activity in human posterior parietal cortex (PPC) and premotor cortex (PMC) during saccades and visually guided reaching using magnetoencephalography (MEG) and novel time-frequency reconstructions of MEG (tfMEG) data. Results indicate that early high-gamma activity over the frontal eye fields (FEFs) was present during saccade preparation, and high-gamma activity progressed from the supplementary and FEFs to visual cortex during saccade execution. In contrast, early high-gamma activity over dorsal PMC and late beta activity in primary motor cortex and PPC were unique to reach preparation. During reaching, high-gamma activity progressed from sensorimotor cortex and PMC to parietooccipital cortex. These unique spatial-temporal processing patterns reflect the known connectivity of 2 different sensorimotor networks in macaques. The onset and duration of activity in these areas provides direct evidence for concurrent serial and parallel processing in the human brain during the integration of the sensorimotor inputs necessary for visually guided performance.

Original languageEnglish (US)
Pages (from-to)519-529
Number of pages11
JournalCerebral Cortex
Volume21
Issue number3
DOIs
StatePublished - Mar 2011

Fingerprint

Motor Cortex
Saccades
Frontal Lobe
Magnetoencephalography
Parietal Lobe
Brain
Macaca
Visual Cortex
Human Activities

Keywords

  • arm
  • magnetoencephalography
  • motor intention
  • parietal
  • premotor
  • saccades

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

Hinkley, L. B. N., Nagarajan, S. S., Dalal, S. S., Guggisberg, A. G., & Disbrow, E. A. (2011). Cortical temporal dynamics of visually guided behavior. Cerebral Cortex, 21(3), 519-529. https://doi.org/10.1093/cercor/bhq102

Cortical temporal dynamics of visually guided behavior. / Hinkley, Leighton B N; Nagarajan, Srikantan S.; Dalal, Sarang S.; Guggisberg, Adrian G.; Disbrow, Elizabeth A.

In: Cerebral Cortex, Vol. 21, No. 3, 03.2011, p. 519-529.

Research output: Contribution to journalArticle

Hinkley, LBN, Nagarajan, SS, Dalal, SS, Guggisberg, AG & Disbrow, EA 2011, 'Cortical temporal dynamics of visually guided behavior', Cerebral Cortex, vol. 21, no. 3, pp. 519-529. https://doi.org/10.1093/cercor/bhq102
Hinkley LBN, Nagarajan SS, Dalal SS, Guggisberg AG, Disbrow EA. Cortical temporal dynamics of visually guided behavior. Cerebral Cortex. 2011 Mar;21(3):519-529. https://doi.org/10.1093/cercor/bhq102
Hinkley, Leighton B N ; Nagarajan, Srikantan S. ; Dalal, Sarang S. ; Guggisberg, Adrian G. ; Disbrow, Elizabeth A. / Cortical temporal dynamics of visually guided behavior. In: Cerebral Cortex. 2011 ; Vol. 21, No. 3. pp. 519-529.
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