Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys

Elizabeth Disbrow, Evangelos Litinas, Gregg H. Recanzone, Jeffrey Padberg, Leah Krubitzer

Research output: Contribution to journalArticle

134 Citations (Scopus)

Abstract

To gain insight into how cortical fields process somatic inputs and ultimately contribute to complex abilities such as tactile object perception, we examined the pattern of connections of two areas in the lateral sulcus of macaque monkeys: the second somatosensory area (S2), and the parietal ventral area (PV). Neuroanatomical tracers were injected into electrophysiologically and/or architectonically defined locations, and labeled cell bodies were identified in cortex ipsilateral and contralateral to the injection site. Transported tracer was related to architectonically defined boundaries so that the full complement of connections of S2 and PV could be appreciated. Our results indicate that S2 is densely interconnected with the primary somatosensory area (3b), PV, and area 7b of the ipsilateral hemisphere, and with S2, 7b, and 3b in the opposite hemisphere. PV is interconnected with areas 3b and 7b, with the parietal rostroventral area, premotor cortex, posterior parietal cortex, and with the medial auditory belt areas. Contralateral connections were restricted to PV in the opposite hemisphere. These data indicate that S2 and PV have unique and overlapping patterns of connections, and that they comprise part of a network that processes both cutaneous and proprioceptive inputs necessary for tactile discrimination and recognition. Although more data are needed, these patterns of interconnections of cortical fields and thalamic nuclei suggest that the somatosensory system may not be segregated into two separate streams of information processing, as has been hypothesized for the visual system. Rather, some fields may be involved in a variety of functions that require motor and sensory integration.

Original languageEnglish (US)
Pages (from-to)382-399
Number of pages18
JournalJournal of Comparative Neurology
Volume462
Issue number4
DOIs
StatePublished - Jul 5 2003

Fingerprint

Touch Perception
Thalamic Nuclei
Parietal Lobe
Auditory Cortex
Aptitude
Somatosensory Cortex
Motor Cortex
Touch
Macaca
Automatic Data Processing
Haplorhini
Skin
Injections
Cell Body
Discrimination (Psychology)
Recognition (Psychology)

Keywords

  • Electrophysiology
  • Primates
  • PV
  • S2
  • Somatosensory cortex
  • Sylvian fissure

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys. / Disbrow, Elizabeth; Litinas, Evangelos; Recanzone, Gregg H.; Padberg, Jeffrey; Krubitzer, Leah.

In: Journal of Comparative Neurology, Vol. 462, No. 4, 05.07.2003, p. 382-399.

Research output: Contribution to journalArticle

Disbrow, Elizabeth ; Litinas, Evangelos ; Recanzone, Gregg H. ; Padberg, Jeffrey ; Krubitzer, Leah. / Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys. In: Journal of Comparative Neurology. 2003 ; Vol. 462, No. 4. pp. 382-399.
@article{dd218544dade43b2a904c2fe330d95a6,
title = "Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys",
abstract = "To gain insight into how cortical fields process somatic inputs and ultimately contribute to complex abilities such as tactile object perception, we examined the pattern of connections of two areas in the lateral sulcus of macaque monkeys: the second somatosensory area (S2), and the parietal ventral area (PV). Neuroanatomical tracers were injected into electrophysiologically and/or architectonically defined locations, and labeled cell bodies were identified in cortex ipsilateral and contralateral to the injection site. Transported tracer was related to architectonically defined boundaries so that the full complement of connections of S2 and PV could be appreciated. Our results indicate that S2 is densely interconnected with the primary somatosensory area (3b), PV, and area 7b of the ipsilateral hemisphere, and with S2, 7b, and 3b in the opposite hemisphere. PV is interconnected with areas 3b and 7b, with the parietal rostroventral area, premotor cortex, posterior parietal cortex, and with the medial auditory belt areas. Contralateral connections were restricted to PV in the opposite hemisphere. These data indicate that S2 and PV have unique and overlapping patterns of connections, and that they comprise part of a network that processes both cutaneous and proprioceptive inputs necessary for tactile discrimination and recognition. Although more data are needed, these patterns of interconnections of cortical fields and thalamic nuclei suggest that the somatosensory system may not be segregated into two separate streams of information processing, as has been hypothesized for the visual system. Rather, some fields may be involved in a variety of functions that require motor and sensory integration.",
keywords = "Electrophysiology, Primates, PV, S2, Somatosensory cortex, Sylvian fissure",
author = "Elizabeth Disbrow and Evangelos Litinas and Recanzone, {Gregg H.} and Jeffrey Padberg and Leah Krubitzer",
year = "2003",
month = "7",
day = "5",
doi = "10.1002/cne.10731",
language = "English (US)",
volume = "462",
pages = "382--399",
journal = "Journal of Comparative Neurology",
issn = "0021-9967",
publisher = "Wiley-Liss Inc.",
number = "4",

}

TY - JOUR

T1 - Cortical connections of the second somatosensory area and the parietal ventral area in macaque monkeys

AU - Disbrow, Elizabeth

AU - Litinas, Evangelos

AU - Recanzone, Gregg H.

AU - Padberg, Jeffrey

AU - Krubitzer, Leah

PY - 2003/7/5

Y1 - 2003/7/5

N2 - To gain insight into how cortical fields process somatic inputs and ultimately contribute to complex abilities such as tactile object perception, we examined the pattern of connections of two areas in the lateral sulcus of macaque monkeys: the second somatosensory area (S2), and the parietal ventral area (PV). Neuroanatomical tracers were injected into electrophysiologically and/or architectonically defined locations, and labeled cell bodies were identified in cortex ipsilateral and contralateral to the injection site. Transported tracer was related to architectonically defined boundaries so that the full complement of connections of S2 and PV could be appreciated. Our results indicate that S2 is densely interconnected with the primary somatosensory area (3b), PV, and area 7b of the ipsilateral hemisphere, and with S2, 7b, and 3b in the opposite hemisphere. PV is interconnected with areas 3b and 7b, with the parietal rostroventral area, premotor cortex, posterior parietal cortex, and with the medial auditory belt areas. Contralateral connections were restricted to PV in the opposite hemisphere. These data indicate that S2 and PV have unique and overlapping patterns of connections, and that they comprise part of a network that processes both cutaneous and proprioceptive inputs necessary for tactile discrimination and recognition. Although more data are needed, these patterns of interconnections of cortical fields and thalamic nuclei suggest that the somatosensory system may not be segregated into two separate streams of information processing, as has been hypothesized for the visual system. Rather, some fields may be involved in a variety of functions that require motor and sensory integration.

AB - To gain insight into how cortical fields process somatic inputs and ultimately contribute to complex abilities such as tactile object perception, we examined the pattern of connections of two areas in the lateral sulcus of macaque monkeys: the second somatosensory area (S2), and the parietal ventral area (PV). Neuroanatomical tracers were injected into electrophysiologically and/or architectonically defined locations, and labeled cell bodies were identified in cortex ipsilateral and contralateral to the injection site. Transported tracer was related to architectonically defined boundaries so that the full complement of connections of S2 and PV could be appreciated. Our results indicate that S2 is densely interconnected with the primary somatosensory area (3b), PV, and area 7b of the ipsilateral hemisphere, and with S2, 7b, and 3b in the opposite hemisphere. PV is interconnected with areas 3b and 7b, with the parietal rostroventral area, premotor cortex, posterior parietal cortex, and with the medial auditory belt areas. Contralateral connections were restricted to PV in the opposite hemisphere. These data indicate that S2 and PV have unique and overlapping patterns of connections, and that they comprise part of a network that processes both cutaneous and proprioceptive inputs necessary for tactile discrimination and recognition. Although more data are needed, these patterns of interconnections of cortical fields and thalamic nuclei suggest that the somatosensory system may not be segregated into two separate streams of information processing, as has been hypothesized for the visual system. Rather, some fields may be involved in a variety of functions that require motor and sensory integration.

KW - Electrophysiology

KW - Primates

KW - PV

KW - S2

KW - Somatosensory cortex

KW - Sylvian fissure

UR - http://www.scopus.com/inward/record.url?scp=0038798666&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0038798666&partnerID=8YFLogxK

U2 - 10.1002/cne.10731

DO - 10.1002/cne.10731

M3 - Article

VL - 462

SP - 382

EP - 399

JO - Journal of Comparative Neurology

JF - Journal of Comparative Neurology

SN - 0021-9967

IS - 4

ER -