Korrelation zwischen der CD4-zahl bei HIV-positiven patienten und radiologischen befunden bei erkrankungen der nasennebenhohlen

Translated title of the contribution: Correlation between CD4 count and radiological findings of disease of the nasal sinuses in HIV-positive patients

J. Mäurer, J. Vlad, Friedrich D Knollmann, R. Schröder, R. Felix

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Background and objective: Sinusitis is a frequent and typical disease in HIV-positive patients. It was the aim of this study to examine retrospectively computed tomograms (CT) and magnetic resonance images (MRI) of such patients for sinusitis. Patients and methods: CT and MRI of the nasal sinuses were retrospectively analysed in 71 HIV-positive patients. Results: Sinusitis was diagnosed in 49 of the 71 patients by conventional radiology (38), CT (13) and/or MRI. In patients with sinusitis, contrary to those without it, there was a significant correlation between progression of the HIV infection, as measured by reduction in CD4 count, and an increased number of symptoms (r = - 0.297; p < 0.05). The latter also correlated significantly with the frequency of concomitant sinusitis (r = 0,336, p < 0.05). The radiological findings correlated more closely with the CD4 count when tomography was used. The correlation coefficient for the number of patients with concomitant sinus disease rose from r = -0.305 to r = -0.459 and for the degree of severity from r = -0.324 to r = -0.484 (p < 0.05). Severity of sinus disease was clearly more marked among HIV-positive than HIV-negative patients. Conclusion: The severity of sinusitis in HIV-positive patients correlated directly with the level of the CD4 count. In these patients tomographic methods are preferable to conventional radiology.

Translated title of the contributionCorrelation between CD4 count and radiological findings of disease of the nasal sinuses in HIV-positive patients
Original languageGerman
Pages (from-to)69-74
Number of pages6
JournalDeutsche Medizinische Wochenschrift
Volume125
Issue number4
StatePublished - Jan 28 2000
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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