Korrelation zwischen der CD4-zahl bei HIV-positiven patienten und radiologischen befunden bei erkrankungen der nasennebenhohlen

Translated title of the contribution: Correlation between CD4 count and radiological findings of disease of the nasal sinuses in HIV-positive patients

J. Mäurer, J. Vlad, Friedrich D Knollmann, R. Schröder, R. Felix

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Background and objective: Sinusitis is a frequent and typical disease in HIV-positive patients. It was the aim of this study to examine retrospectively computed tomograms (CT) and magnetic resonance images (MRI) of such patients for sinusitis. Patients and methods: CT and MRI of the nasal sinuses were retrospectively analysed in 71 HIV-positive patients. Results: Sinusitis was diagnosed in 49 of the 71 patients by conventional radiology (38), CT (13) and/or MRI. In patients with sinusitis, contrary to those without it, there was a significant correlation between progression of the HIV infection, as measured by reduction in CD4 count, and an increased number of symptoms (r = - 0.297; p < 0.05). The latter also correlated significantly with the frequency of concomitant sinusitis (r = 0,336, p < 0.05). The radiological findings correlated more closely with the CD4 count when tomography was used. The correlation coefficient for the number of patients with concomitant sinus disease rose from r = -0.305 to r = -0.459 and for the degree of severity from r = -0.324 to r = -0.484 (p < 0.05). Severity of sinus disease was clearly more marked among HIV-positive than HIV-negative patients. Conclusion: The severity of sinusitis in HIV-positive patients correlated directly with the level of the CD4 count. In these patients tomographic methods are preferable to conventional radiology.

Original languageGerman
Pages (from-to)69-74
Number of pages6
JournalDeutsche Medizinische Wochenschrift
Volume125
Issue number4
StatePublished - Jan 28 2000
Externally publishedYes

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Paranasal Sinuses
CD4 Lymphocyte Count
HIV
Sinusitis
Magnetic Resonance Spectroscopy
Radiology
HIV Infections
Tomography

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Korrelation zwischen der CD4-zahl bei HIV-positiven patienten und radiologischen befunden bei erkrankungen der nasennebenhohlen. / Mäurer, J.; Vlad, J.; Knollmann, Friedrich D; Schröder, R.; Felix, R.

In: Deutsche Medizinische Wochenschrift, Vol. 125, No. 4, 28.01.2000, p. 69-74.

Research output: Contribution to journalArticle

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abstract = "Background and objective: Sinusitis is a frequent and typical disease in HIV-positive patients. It was the aim of this study to examine retrospectively computed tomograms (CT) and magnetic resonance images (MRI) of such patients for sinusitis. Patients and methods: CT and MRI of the nasal sinuses were retrospectively analysed in 71 HIV-positive patients. Results: Sinusitis was diagnosed in 49 of the 71 patients by conventional radiology (38), CT (13) and/or MRI. In patients with sinusitis, contrary to those without it, there was a significant correlation between progression of the HIV infection, as measured by reduction in CD4 count, and an increased number of symptoms (r = - 0.297; p < 0.05). The latter also correlated significantly with the frequency of concomitant sinusitis (r = 0,336, p < 0.05). The radiological findings correlated more closely with the CD4 count when tomography was used. The correlation coefficient for the number of patients with concomitant sinus disease rose from r = -0.305 to r = -0.459 and for the degree of severity from r = -0.324 to r = -0.484 (p < 0.05). Severity of sinus disease was clearly more marked among HIV-positive than HIV-negative patients. Conclusion: The severity of sinusitis in HIV-positive patients correlated directly with the level of the CD4 count. In these patients tomographic methods are preferable to conventional radiology.",
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