Correction of hemifacial atrophy with autologous fat transplantation

Yun Xie, Qingfeng Li, Danning Zheng, Hua Lei, Lee Li-Qun Pu

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


BACKGROUND: Autologous fat transplantation has frequently been used by many surgeons for facial recontouring in esthetic patients, with good long-term results. However, this technique has not been used primarily in treating patients with hemifacial atrophy, and its efficacy and long-term outcome remain unknown. METHODS: In a 7-year period, 31 patients with hemifacial atrophy were treated with autologous fat transplantation in our institution. All patients had been in their stable phase of the disease for at least 1 year. Autologous fat grafts were harvested from the lower abdomen or thigh with our preferred low-pressure syringe technique and then spun at the lower speed. The fat grafts were injected into multiple areas in multiple tissue planes and tunnels to the diseased side of the face. The same procedure was repeated once or twice as necessary after each injection in at least 3 months. All patients were followed up to 5 years, and their outcomes were evaluated by the patients, plastic surgeons, and laypersons separately. RESULTS: Obviously improved facial contour was evident in most patients after autologous fat transplantations. More than 65% of the patients in this series were assessed as satisfactory by all 3 groups. Between 10% and 30% of the patients were mostly satisfactory. Only less than 7% of the patients were unsatisfactory. No complications were seen in either donor sites or recipient sites in this series. CONCLUSIONS: Autologous fat transplantation can be a good treatment of choice for patients with hemifacial atrophy.

Original languageEnglish (US)
Pages (from-to)645-653
Number of pages9
JournalAnnals of Plastic Surgery
Issue number6
StatePublished - Dec 2007
Externally publishedYes


  • Autologous fat transplantation
  • Fat injection
  • Free fat grafting
  • Progressive hemifacial atrophy
  • Romberg disease

ASJC Scopus subject areas

  • Surgery


Dive into the research topics of 'Correction of hemifacial atrophy with autologous fat transplantation'. Together they form a unique fingerprint.

Cite this