Coronary bypass surgery for unstable angina pectoris: Results of nonrandomized studies

R. R. Miller, Ezra A Amsterdam, A. N. DeMaria, D. T. Mason

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Unstable angina is a commonly encountered clinical condition of considerable importance in that it presages subsequent morbidity and mortality in substantial numbers of coronary patients. This syndrome (also termed coronary insufficiency, preinfarction angina, intermediate coronary syndrome, and crescendo angina) is defined in the present discussion as angina pectoris occurring at rest, unresponsive to nitroglycerin, persisting at least 20 minutes, and accompanied by electrocardiographic evidence of ischemia without enzymatic confirmation of myocardial necrosis. Despite the significance of the preinfarction angina syndrome, accumulation of long-term followup data sufficient to afford meaningful conclusions concerning the most efficacious management are only beginning to become available. Thus improved decisions of selection of patients for medical management or coronary bypass surgery are now possible. The purpose of this report is to consider the results of nonrandomized studies of unstable angina relative to medical and surgical management.

Original languageEnglish (US)
Pages (from-to)189-200
Number of pages12
JournalCardiovascular Clinics
Issue number2
StatePublished - 1977

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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