Abstract
Objective: To describe the clinical presentation, treatment, and outcome of four horses with severe corneal edema caused by suspected endothelial disease treated with a superficial keratectomy and Gundersen inlay flap and to determine whether this procedure (i) reduces corneal edema, (ii) reduces ocular pain, (iii) eliminates recurrent corneal ulceration, and (iv) improves vision in these horses. Animals studied: Four horses met inclusion criterion of (i) diagnosis with endothelial disease by a board-certified veterinary ophthalmologist and (ii) surgical treatment with a superficial keratectomy and Gundersen inlay flap. Procedure: Retrospective medical record review of included horses was used to determine breed, age and sex of included horses, as well as details of medical and surgical therapy, and visual outcome. Results: Four horses were presented with a complaint of focal corneal edema that progressed to diffuse corneal edema. Epithelial bullae and ulceration were present in all cases. The disease process was unresponsive to standard medical treatment with a hyperosmotic agent and topical and systemic anti-inflammatories. However, treatment with a superficial keratectomy and Gundersen inlay flap performed under general anesthesia was associated with (i) a significant decrease in corneal edema, (ii) increased comfort, (iii) elimination of corneal ulceration, and (iv) retention of vision postoperatively with little to no need for medical therapy. Follow-up time was 15, 12, 6, and 3 months. Conclusions: The superficial keratectomy and Gundersen inlay flap may provide a surgical alternative to chronic medical treatment of severe corneal edema in horses.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 65-72 |
| Number of pages | 8 |
| Journal | Veterinary Ophthalmology |
| Volume | 20 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 1 2017 |
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Keywords
- conjunctival graft
- corneal edema
- Gundersen inlay flap
- horse
- superficial keratectomy
ASJC Scopus subject areas
- veterinary(all)
Cite this
Corneal edema in four horses treated with a superficial keratectomy and Gundersen inlay flap. / Scherrer, Nicole M.; Utter, Mary; Miller, William W.
In: Veterinary Ophthalmology, Vol. 20, No. 1, 01.01.2017, p. 65-72.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Corneal edema in four horses treated with a superficial keratectomy and Gundersen inlay flap
AU - Scherrer, Nicole M.
AU - Utter, Mary
AU - Miller, William W.
PY - 2017/1/1
Y1 - 2017/1/1
N2 - Objective: To describe the clinical presentation, treatment, and outcome of four horses with severe corneal edema caused by suspected endothelial disease treated with a superficial keratectomy and Gundersen inlay flap and to determine whether this procedure (i) reduces corneal edema, (ii) reduces ocular pain, (iii) eliminates recurrent corneal ulceration, and (iv) improves vision in these horses. Animals studied: Four horses met inclusion criterion of (i) diagnosis with endothelial disease by a board-certified veterinary ophthalmologist and (ii) surgical treatment with a superficial keratectomy and Gundersen inlay flap. Procedure: Retrospective medical record review of included horses was used to determine breed, age and sex of included horses, as well as details of medical and surgical therapy, and visual outcome. Results: Four horses were presented with a complaint of focal corneal edema that progressed to diffuse corneal edema. Epithelial bullae and ulceration were present in all cases. The disease process was unresponsive to standard medical treatment with a hyperosmotic agent and topical and systemic anti-inflammatories. However, treatment with a superficial keratectomy and Gundersen inlay flap performed under general anesthesia was associated with (i) a significant decrease in corneal edema, (ii) increased comfort, (iii) elimination of corneal ulceration, and (iv) retention of vision postoperatively with little to no need for medical therapy. Follow-up time was 15, 12, 6, and 3 months. Conclusions: The superficial keratectomy and Gundersen inlay flap may provide a surgical alternative to chronic medical treatment of severe corneal edema in horses.
AB - Objective: To describe the clinical presentation, treatment, and outcome of four horses with severe corneal edema caused by suspected endothelial disease treated with a superficial keratectomy and Gundersen inlay flap and to determine whether this procedure (i) reduces corneal edema, (ii) reduces ocular pain, (iii) eliminates recurrent corneal ulceration, and (iv) improves vision in these horses. Animals studied: Four horses met inclusion criterion of (i) diagnosis with endothelial disease by a board-certified veterinary ophthalmologist and (ii) surgical treatment with a superficial keratectomy and Gundersen inlay flap. Procedure: Retrospective medical record review of included horses was used to determine breed, age and sex of included horses, as well as details of medical and surgical therapy, and visual outcome. Results: Four horses were presented with a complaint of focal corneal edema that progressed to diffuse corneal edema. Epithelial bullae and ulceration were present in all cases. The disease process was unresponsive to standard medical treatment with a hyperosmotic agent and topical and systemic anti-inflammatories. However, treatment with a superficial keratectomy and Gundersen inlay flap performed under general anesthesia was associated with (i) a significant decrease in corneal edema, (ii) increased comfort, (iii) elimination of corneal ulceration, and (iv) retention of vision postoperatively with little to no need for medical therapy. Follow-up time was 15, 12, 6, and 3 months. Conclusions: The superficial keratectomy and Gundersen inlay flap may provide a surgical alternative to chronic medical treatment of severe corneal edema in horses.
KW - conjunctival graft
KW - corneal edema
KW - Gundersen inlay flap
KW - horse
KW - superficial keratectomy
UR - http://www.scopus.com/inward/record.url?scp=84955121609&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84955121609&partnerID=8YFLogxK
U2 - 10.1111/vop.12342
DO - 10.1111/vop.12342
M3 - Article
C2 - 26778407
AN - SCOPUS:84955121609
VL - 20
SP - 65
EP - 72
JO - Veterinary Ophthalmology
JF - Veterinary Ophthalmology
SN - 1463-5216
IS - 1
ER -