Mice homozygous for the mtutant gene quaking (qk) with a high frequency of axial tremors had a low concentration of copper in the brain. Supplementation during pregnancy and lactation with a high level of dietary copper greatly reduced the frequency of tremors and brought brain copper level to normal in the offspring. It is suggested that qk affects copper metabolism.
|Original language||English (US)|
|Number of pages||3|
|State||Published - 1976|
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