Controlled localized thrombolysis with the "Turbo" Trellis to treat acute arterial occlusions following major surgery

Frank R. Arko, Eugene S Lee, Christopher K. Zarins, Thomas J. Fogarty

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

Purpose: To present the management of acute arterial ischemia following major abdominal and orthopedic surgery using a percutaneous thrombectomy device and a low dose of thrombolytic agent. Case Report: A 38-year-old woman with T-8 paraplegia from a traumatic fall developed pelvic osteomyelitis, for which a left hemipelvectomy, hysterectomy, and partial vaginal resection were performed. Twelve hours after the procedure, the patient developed an ischemic left leg. Computed tomographic angiography demonstrated an occlusion of the left external iliac and common femoral arteries. A Turbo Trellis percutaneous thrombectomy device was used to lyse the left external iliac artery thrombosis using 1 mg of tissue plasminogen activator infused between the proximal and distal occluding balloons of the device. Total dispersion time was 5 minutes. There was complete thrombus removal without any significant bleeding complications. At 6 months, the artery remains widely patent. Conclusions: Combination therapy with mechanical thrombectomy devices and low dose thrombolytic agents can be used to treat acute arterial occlusions at a single setting. The increased speed of the Turbo Trellis may allow for smaller doses of thrombolytic agents and shorter treatment times.

Original languageEnglish (US)
Pages (from-to)339-343
Number of pages5
JournalJournal of Endovascular Therapy
Volume11
Issue number3
DOIs
StatePublished - Jun 2004
Externally publishedYes

Fingerprint

Thrombectomy
Fibrinolytic Agents
Equipment and Supplies
Thrombosis
Hemipelvectomy
Vaginal Hysterectomy
Iliac Artery
Paraplegia
Tissue Plasminogen Activator
Osteomyelitis
Femoral Artery
Orthopedics
Leg
Angiography
Ischemia
Arteries
Hemorrhage
Therapeutics

Keywords

  • Acute critical limb ischemia
  • Common femoral artery
  • External iliac artery
  • Percutaneous thrombectomy
  • Thrombolysis
  • Thrombosis
  • Tissue plasminogen activator

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Controlled localized thrombolysis with the "Turbo" Trellis to treat acute arterial occlusions following major surgery. / Arko, Frank R.; Lee, Eugene S; Zarins, Christopher K.; Fogarty, Thomas J.

In: Journal of Endovascular Therapy, Vol. 11, No. 3, 06.2004, p. 339-343.

Research output: Contribution to journalArticle

@article{ea7fbc9e988147d897a1a4d9dae791f2,
title = "Controlled localized thrombolysis with the {"}Turbo{"} Trellis to treat acute arterial occlusions following major surgery",
abstract = "Purpose: To present the management of acute arterial ischemia following major abdominal and orthopedic surgery using a percutaneous thrombectomy device and a low dose of thrombolytic agent. Case Report: A 38-year-old woman with T-8 paraplegia from a traumatic fall developed pelvic osteomyelitis, for which a left hemipelvectomy, hysterectomy, and partial vaginal resection were performed. Twelve hours after the procedure, the patient developed an ischemic left leg. Computed tomographic angiography demonstrated an occlusion of the left external iliac and common femoral arteries. A Turbo Trellis percutaneous thrombectomy device was used to lyse the left external iliac artery thrombosis using 1 mg of tissue plasminogen activator infused between the proximal and distal occluding balloons of the device. Total dispersion time was 5 minutes. There was complete thrombus removal without any significant bleeding complications. At 6 months, the artery remains widely patent. Conclusions: Combination therapy with mechanical thrombectomy devices and low dose thrombolytic agents can be used to treat acute arterial occlusions at a single setting. The increased speed of the Turbo Trellis may allow for smaller doses of thrombolytic agents and shorter treatment times.",
keywords = "Acute critical limb ischemia, Common femoral artery, External iliac artery, Percutaneous thrombectomy, Thrombolysis, Thrombosis, Tissue plasminogen activator",
author = "Arko, {Frank R.} and Lee, {Eugene S} and Zarins, {Christopher K.} and Fogarty, {Thomas J.}",
year = "2004",
month = "6",
doi = "10.1583/03-1146.1",
language = "English (US)",
volume = "11",
pages = "339--343",
journal = "Journal of Endovascular Therapy",
issn = "1526-6028",
publisher = "International Society of Endovascular Specialists",
number = "3",

}

TY - JOUR

T1 - Controlled localized thrombolysis with the "Turbo" Trellis to treat acute arterial occlusions following major surgery

AU - Arko, Frank R.

AU - Lee, Eugene S

AU - Zarins, Christopher K.

AU - Fogarty, Thomas J.

PY - 2004/6

Y1 - 2004/6

N2 - Purpose: To present the management of acute arterial ischemia following major abdominal and orthopedic surgery using a percutaneous thrombectomy device and a low dose of thrombolytic agent. Case Report: A 38-year-old woman with T-8 paraplegia from a traumatic fall developed pelvic osteomyelitis, for which a left hemipelvectomy, hysterectomy, and partial vaginal resection were performed. Twelve hours after the procedure, the patient developed an ischemic left leg. Computed tomographic angiography demonstrated an occlusion of the left external iliac and common femoral arteries. A Turbo Trellis percutaneous thrombectomy device was used to lyse the left external iliac artery thrombosis using 1 mg of tissue plasminogen activator infused between the proximal and distal occluding balloons of the device. Total dispersion time was 5 minutes. There was complete thrombus removal without any significant bleeding complications. At 6 months, the artery remains widely patent. Conclusions: Combination therapy with mechanical thrombectomy devices and low dose thrombolytic agents can be used to treat acute arterial occlusions at a single setting. The increased speed of the Turbo Trellis may allow for smaller doses of thrombolytic agents and shorter treatment times.

AB - Purpose: To present the management of acute arterial ischemia following major abdominal and orthopedic surgery using a percutaneous thrombectomy device and a low dose of thrombolytic agent. Case Report: A 38-year-old woman with T-8 paraplegia from a traumatic fall developed pelvic osteomyelitis, for which a left hemipelvectomy, hysterectomy, and partial vaginal resection were performed. Twelve hours after the procedure, the patient developed an ischemic left leg. Computed tomographic angiography demonstrated an occlusion of the left external iliac and common femoral arteries. A Turbo Trellis percutaneous thrombectomy device was used to lyse the left external iliac artery thrombosis using 1 mg of tissue plasminogen activator infused between the proximal and distal occluding balloons of the device. Total dispersion time was 5 minutes. There was complete thrombus removal without any significant bleeding complications. At 6 months, the artery remains widely patent. Conclusions: Combination therapy with mechanical thrombectomy devices and low dose thrombolytic agents can be used to treat acute arterial occlusions at a single setting. The increased speed of the Turbo Trellis may allow for smaller doses of thrombolytic agents and shorter treatment times.

KW - Acute critical limb ischemia

KW - Common femoral artery

KW - External iliac artery

KW - Percutaneous thrombectomy

KW - Thrombolysis

KW - Thrombosis

KW - Tissue plasminogen activator

UR - http://www.scopus.com/inward/record.url?scp=3042611873&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=3042611873&partnerID=8YFLogxK

U2 - 10.1583/03-1146.1

DO - 10.1583/03-1146.1

M3 - Article

C2 - 15174917

AN - SCOPUS:3042611873

VL - 11

SP - 339

EP - 343

JO - Journal of Endovascular Therapy

JF - Journal of Endovascular Therapy

SN - 1526-6028

IS - 3

ER -