Contribution of facet joints, axial compression, and composition to human lumbar disc torsion mechanics

Semih E. Bezci, Ananth Eleswarapu, Eric Otto Klineberg, Grace D. O'Connell

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Stresses applied to the spinal column are distributed between the intervertebral disc and facet joints. Structural and compositional changes alter stress distributions within the disc and between the disc and facet joints. These changes influence the mechanical properties of the disc joint, including its stiffness, range of motion, and energy absorption under quasi-static and dynamic loads. There have been few studies evaluating the role of facet joints in torsion. Furthermore, the relationship between biochemical composition and torsion mechanics is not well understood. Therefore, the first objective of this study was to investigate the role of facet joints in torsion mechanics of healthy and degenerated human lumbar discs under a wide range of compressive preloads. To achieve this, each disc was tested under four different compressive preloads (300-1200N) with and without facet joints. The second objective was to develop a quantitative structure-function relationship between tissue composition and torsion mechanics. Facet joints have a significant contribution to disc torsional stiffness (∼60%) and viscoelasticity, regardless of the magnitude of axial compression. The findings from this study demonstrate that annulus fibrosus GAG content plays an important role in disc torsion mechanics. A decrease in GAG content with degeneration reduced torsion mechanics by more than an order of magnitude, while collagen content did not significantly influence disc torsion mechanics. The biochemical-mechanical and compression-torsion relationships reported in this study allow for better comparison between studies that use discs of varying levels of degeneration or testing protocols and provide important design criteria for biological repair strategies.

Original languageEnglish (US)
JournalJournal of Orthopaedic Research
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Zygapophyseal Joint
Mechanics
Mechanical Torsion
Intervertebral Disc
Articular Range of Motion
Spine
Collagen
Joints

Keywords

  • Composition
  • Degeneration
  • Facet joints
  • Intervertebral disc
  • Torsion

ASJC Scopus subject areas

  • Orthopedics and Sports Medicine

Cite this

Contribution of facet joints, axial compression, and composition to human lumbar disc torsion mechanics. / Bezci, Semih E.; Eleswarapu, Ananth; Klineberg, Eric Otto; O'Connell, Grace D.

In: Journal of Orthopaedic Research, 01.01.2018.

Research output: Contribution to journalArticle

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