Contrast-enhanced high resolution magnetic resonance imaging of skin tumours

Jürgen Mäurer, Friedrich D Knollmann, Carsten William, Ralf Schröder, Thomas J. Vogl, Jürgen Bier, Roland Felix

Research output: Contribution to journalArticlepeer-review


Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.

Original languageEnglish (US)
Pages (from-to)43-50
Number of pages8
Issue number1
StatePublished - 1997
Externally publishedYes


  • Gd-DTPA
  • High resolution MRI
  • Skin
  • Skin tumours
  • Surface coil

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Radiology Nuclear Medicine and imaging


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