Abstract
Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.
Original language | English (US) |
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Pages (from-to) | 43-50 |
Number of pages | 8 |
Journal | Radiography |
Volume | 3 |
Issue number | 1 |
State | Published - 1997 |
Externally published | Yes |
Keywords
- Gd-DTPA
- High resolution MRI
- Skin
- Skin tumours
- Surface coil
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Radiology Nuclear Medicine and imaging