Contrast-enhanced high resolution magnetic resonance imaging of skin tumours

Jürgen Mäurer; Friedrich D Knollmann; Carsten William; Ralf Schröder; Thomas J. Vogl; Jürgen Bier; Roland Felix

Contrast-enhanced high resolution magnetic resonance imaging of skin tumours

Jürgen Mäurer, Friedrich D Knollmann, Carsten William, Ralf Schröder, Thomas J. Vogl, Jürgen Bier, Roland Felix

Research output: Contribution to journal › Article › peer-review

Abstract

Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg^-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.

Original language	English (US)
Pages (from-to)	43-50
Number of pages	8
Journal	Radiography
Volume	3
Issue number	1
State	Published - 1997
Externally published	Yes

Keywords

Gd-DTPA
High resolution MRI
Skin
Skin tumours
Surface coil

ASJC Scopus subject areas

Pathology and Forensic Medicine
Radiology Nuclear Medicine and imaging

Cite this

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title = "Contrast-enhanced high resolution magnetic resonance imaging of skin tumours",

abstract = "Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.",

keywords = "Gd-DTPA, High resolution MRI, Skin, Skin tumours, Surface coil",

author = "J{\"u}rgen M{\"a}urer and Knollmann, {Friedrich D} and Carsten William and Ralf Schr{\"o}der and Vogl, {Thomas J.} and J{\"u}rgen Bier and Roland Felix",

year = "1997",

language = "English (US)",

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journal = "Radiography",

issn = "1078-8174",

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TY - JOUR

T1 - Contrast-enhanced high resolution magnetic resonance imaging of skin tumours

AU - Mäurer, Jürgen

AU - Knollmann, Friedrich D

AU - William, Carsten

AU - Schröder, Ralf

AU - Vogl, Thomas J.

AU - Bier, Jürgen

AU - Felix, Roland

PY - 1997

Y1 - 1997

N2 - Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.

AB - Purpose: To evaluate the use of Gd-DTPA in imaging epithelial skin tumours and tumour-like lesions, 45 benign and 18 malignant skin tumours were prospectively examined by high resolution magnetic resonance imaging (MRI) at 1.5 T using a 2.5 cm surface coil. Methods: For tumour assessment, transverse plain and contrast-enhanced scans (0.1 mmol kg-1 Gd-DTPA) were performed (TR 500 ms, TE 25 ms, three acquisitions, 256 x 256 matrix, FOV 2.5 cm). Results: Contrast enhancement (CE) was quantitatively determined as the percentage enhancement of signal intensity. Histological findings were correlated using a Wilcoxon test (P < 0.05). Quality of contrast enhancement was independently assessed by three investigators, who mostly described inhomogenous enhancement, regardless of histological findings. Conclusions: Malignant tumours could not be differentiated from benign lesions by contrast enhancement. MRI using Gd-DTPA does not differentiate skin tumour types.

KW - Gd-DTPA

KW - High resolution MRI

KW - Skin

KW - Skin tumours

KW - Surface coil

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Contrast-enhanced high resolution magnetic resonance imaging of skin tumours

Abstract

Keywords

ASJC Scopus subject areas

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