Contrast-enhanced computed tomography as a preoperative indicator of vascular invasion from adrenal masses in dogs

Ryan M. Schultz, Erik R Wisner, Eric G Johnson, Jennifer S. MacLeod

Research output: Contribution to journalArticle

44 Citations (Scopus)

Abstract

The purpose of this study was to determine if contrast-enhanced computed tomography (CT) accurately reflected vascular luminal invasion by adrenal masses in dogs. Medical records of 15 dogs with 17 adrenal masses that underwent preoperative CT imaging were reviewed. Presence or absence of vascular invasion was confirmed by surgery or necropsy/histology. Vascular invasion was identified correctly using contrast-enhanced CT in 11/12 dogs. The sensitivity and specificity of contrast-enhanced CT for vascular invasion compared with surgery or necropsy was 92% and 100%, respectively. The positive predictive value and negative predictive value of contrast-enhanced CT was 100% and 90%, respectively. The accuracy was 95%. In one dog, invasion of the phrenicoabdominal vein was not identified on CT images. Six of eight masses with vascular invasion where a histologic diagnosis was obtained were malignant. Four of four pheochromocytomas invaded adjacent vasculature. Contrast-enhanced CT provided accurate preoperative assessment of adrenal masses. Vascular invasion by adrenal masses in this study occurred by way of the lumen of the phrenicoabdominal vein with subsequent intraluminal extension into other veins, rather than by erosion through vessel walls.

Original languageEnglish (US)
Pages (from-to)625-629
Number of pages5
JournalVeterinary Radiology and Ultrasound
Volume50
Issue number6
DOIs
StatePublished - Nov 2009

Fingerprint

computed tomography
blood vessels
Blood Vessels
Tomography
Dogs
dogs
Veins
necropsy
surgery
Pheochromocytoma
histology
Medical Records
Histology
image analysis
Sensitivity and Specificity

Keywords

  • Adrenalectomy
  • Canine
  • Computed tomography
  • Pheochromocytoma
  • Phrenicoabdominal
  • Tumor thrombus

ASJC Scopus subject areas

  • veterinary(all)

Cite this

Contrast-enhanced computed tomography as a preoperative indicator of vascular invasion from adrenal masses in dogs. / Schultz, Ryan M.; Wisner, Erik R; Johnson, Eric G; MacLeod, Jennifer S.

In: Veterinary Radiology and Ultrasound, Vol. 50, No. 6, 11.2009, p. 625-629.

Research output: Contribution to journalArticle

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