Contrast detection in infants with fragile X syndrome

F. Farzin, D. Whitney, Randi J Hagerman, S. M. Rivera

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

Studies have reported that a selective deficit in visual motion processing is present in certain developmental disorders, including Williams syndrome and autism. More recent evidence suggests a visual motion impairment is also present in adults with fragile X syndrome (FXS), the most common form of inherited mental retardation. The goal of the current study was to examine low-level cortical visual processing in infants diagnosed with FXS in order to explore the developmental origin of this putative deficit. We measured contrast detection of first-order (luminance-defined) and second-order (contrast-defined) gratings at two levels of temporal frequency, 0 Hz (static) and 4 Hz (moving). Results indicate that infants with FXS display significantly higher detection thresholds only for the second-order, moving stimuli compared to mental age-matched typically developing controls.

Original languageEnglish (US)
Pages (from-to)1471-1478
Number of pages8
JournalVision Research
Volume48
Issue number13
DOIs
StatePublished - Jun 2008

Fingerprint

Fragile X Syndrome
Williams Syndrome
Vision Disorders
Autistic Disorder
Intellectual Disability

Keywords

  • Contrast detection
  • Forced-choice preferential looking
  • Fragile X syndrome
  • Motion
  • Second-order
  • Threshold

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems

Cite this

Contrast detection in infants with fragile X syndrome. / Farzin, F.; Whitney, D.; Hagerman, Randi J; Rivera, S. M.

In: Vision Research, Vol. 48, No. 13, 06.2008, p. 1471-1478.

Research output: Contribution to journalArticle

Farzin, F. ; Whitney, D. ; Hagerman, Randi J ; Rivera, S. M. / Contrast detection in infants with fragile X syndrome. In: Vision Research. 2008 ; Vol. 48, No. 13. pp. 1471-1478.
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