Contemporary surgical management of cardiac paragangliomas

Basel Ramlawi; Elizabeth David; Min P. Kim; Luis J. Garcia-Morales; Shanda H. Blackmon; David C. Rice; Ara A. Vaporciyan; Michael J. Reardon

doi:10.1016/j.athoracsur.2012.02.040

Contemporary surgical management of cardiac paragangliomas

Basel Ramlawi, Elizabeth David, Min P. Kim, Luis J. Garcia-Morales, Shanda H. Blackmon, David C. Rice, Ara A. Vaporciyan, Michael J. Reardon

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

Original language	English (US)
Pages (from-to)	1972-1976
Number of pages	5
Journal	Annals of Thoracic Surgery
Volume	93
Issue number	6
DOIs	https://doi.org/10.1016/j.athoracsur.2012.02.040
State	Published - Jun 1 2012
Externally published	Yes

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Surgery
Pulmonary and Respiratory Medicine

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10.1016/j.athoracsur.2012.02.040

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title = "Contemporary surgical management of cardiac paragangliomas",

abstract = "Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.",

author = "Basel Ramlawi and Elizabeth David and Kim, {Min P.} and Garcia-Morales, {Luis J.} and Blackmon, {Shanda H.} and Rice, {David C.} and Vaporciyan, {Ara A.} and Reardon, {Michael J.}",

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AU - Ramlawi, Basel

AU - David, Elizabeth

AU - Kim, Min P.

AU - Garcia-Morales, Luis J.

AU - Blackmon, Shanda H.

AU - Rice, David C.

AU - Vaporciyan, Ara A.

AU - Reardon, Michael J.

PY - 2012/6/1

Y1 - 2012/6/1

N2 - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

AB - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

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Contemporary surgical management of cardiac paragangliomas

Abstract

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