Contemporary surgical management of cardiac paragangliomas

Basel Ramlawi, Elizabeth David, Min P. Kim, Luis J. Garcia-Morales, Shanda H. Blackmon, David C. Rice, Ara A. Vaporciyan, Michael J. Reardon

Research output: Contribution to journalArticlepeer-review

39 Scopus citations

Abstract

Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

Original languageEnglish (US)
Pages (from-to)1972-1976
Number of pages5
JournalAnnals of Thoracic Surgery
Volume93
Issue number6
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

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