Contemporary surgical management of cardiac paragangliomas

Basel Ramlawi, Elizabeth David, Min P. Kim, Luis J. Garcia-Morales, Shanda H. Blackmon, David C. Rice, Ara A. Vaporciyan, Michael J. Reardon

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

Original languageEnglish (US)
Pages (from-to)1972-1976
Number of pages5
JournalAnnals of Thoracic Surgery
Volume93
Issue number6
DOIs
StatePublished - Jun 1 2012
Externally publishedYes

Fingerprint

Paraganglioma
Chromaffin Cells
Autologous Transplantation
Neural Crest
Hospital Mortality
Heart Atria
Cardiopulmonary Bypass
Hemorrhage
Neoplasms
Therapeutics

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Ramlawi, B., David, E., Kim, M. P., Garcia-Morales, L. J., Blackmon, S. H., Rice, D. C., ... Reardon, M. J. (2012). Contemporary surgical management of cardiac paragangliomas. Annals of Thoracic Surgery, 93(6), 1972-1976. https://doi.org/10.1016/j.athoracsur.2012.02.040

Contemporary surgical management of cardiac paragangliomas. / Ramlawi, Basel; David, Elizabeth; Kim, Min P.; Garcia-Morales, Luis J.; Blackmon, Shanda H.; Rice, David C.; Vaporciyan, Ara A.; Reardon, Michael J.

In: Annals of Thoracic Surgery, Vol. 93, No. 6, 01.06.2012, p. 1972-1976.

Research output: Contribution to journalArticle

Ramlawi, B, David, E, Kim, MP, Garcia-Morales, LJ, Blackmon, SH, Rice, DC, Vaporciyan, AA & Reardon, MJ 2012, 'Contemporary surgical management of cardiac paragangliomas', Annals of Thoracic Surgery, vol. 93, no. 6, pp. 1972-1976. https://doi.org/10.1016/j.athoracsur.2012.02.040
Ramlawi B, David E, Kim MP, Garcia-Morales LJ, Blackmon SH, Rice DC et al. Contemporary surgical management of cardiac paragangliomas. Annals of Thoracic Surgery. 2012 Jun 1;93(6):1972-1976. https://doi.org/10.1016/j.athoracsur.2012.02.040
Ramlawi, Basel ; David, Elizabeth ; Kim, Min P. ; Garcia-Morales, Luis J. ; Blackmon, Shanda H. ; Rice, David C. ; Vaporciyan, Ara A. ; Reardon, Michael J. / Contemporary surgical management of cardiac paragangliomas. In: Annals of Thoracic Surgery. 2012 ; Vol. 93, No. 6. pp. 1972-1976.
@article{cdb4dbbcfa784b20bfbd68f81535fb34,
title = "Contemporary surgical management of cardiac paragangliomas",
abstract = "Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14{\%}. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.",
author = "Basel Ramlawi and Elizabeth David and Kim, {Min P.} and Garcia-Morales, {Luis J.} and Blackmon, {Shanda H.} and Rice, {David C.} and Vaporciyan, {Ara A.} and Reardon, {Michael J.}",
year = "2012",
month = "6",
day = "1",
doi = "10.1016/j.athoracsur.2012.02.040",
language = "English (US)",
volume = "93",
pages = "1972--1976",
journal = "Annals of Thoracic Surgery",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "6",

}

TY - JOUR

T1 - Contemporary surgical management of cardiac paragangliomas

AU - Ramlawi, Basel

AU - David, Elizabeth

AU - Kim, Min P.

AU - Garcia-Morales, Luis J.

AU - Blackmon, Shanda H.

AU - Rice, David C.

AU - Vaporciyan, Ara A.

AU - Reardon, Michael J.

PY - 2012/6/1

Y1 - 2012/6/1

N2 - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

AB - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.

UR - http://www.scopus.com/inward/record.url?scp=84861646026&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84861646026&partnerID=8YFLogxK

U2 - 10.1016/j.athoracsur.2012.02.040

DO - 10.1016/j.athoracsur.2012.02.040

M3 - Article

C2 - 22537533

AN - SCOPUS:84861646026

VL - 93

SP - 1972

EP - 1976

JO - Annals of Thoracic Surgery

JF - Annals of Thoracic Surgery

SN - 0003-4975

IS - 6

ER -