Abstract
Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1972-1976 |
| Number of pages | 5 |
| Journal | Annals of Thoracic Surgery |
| Volume | 93 |
| Issue number | 6 |
| DOIs | |
| State | Published - Jun 1 2012 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine
- Surgery
- Pulmonary and Respiratory Medicine
Cite this
Contemporary surgical management of cardiac paragangliomas. / Ramlawi, Basel; David, Elizabeth; Kim, Min P.; Garcia-Morales, Luis J.; Blackmon, Shanda H.; Rice, David C.; Vaporciyan, Ara A.; Reardon, Michael J.
In: Annals of Thoracic Surgery, Vol. 93, No. 6, 01.06.2012, p. 1972-1976.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Contemporary surgical management of cardiac paragangliomas
AU - Ramlawi, Basel
AU - David, Elizabeth
AU - Kim, Min P.
AU - Garcia-Morales, Luis J.
AU - Blackmon, Shanda H.
AU - Rice, David C.
AU - Vaporciyan, Ara A.
AU - Reardon, Michael J.
PY - 2012/6/1
Y1 - 2012/6/1
N2 - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
AB - Background: Cardiac paragangliomas are an extremely rare subset of chromaffin cell tumors that develop from neural crest cells. Methods: Between March 2004 and October 2010, 7 male patients from our two institutions who underwent surgical resection of cardiac paraganglioma were retrospectively reviewed. Results: In 5 patients, paragangliomas originated from the roof of the left atrium, and in 2 patients, they originated from the aortic root. Hospital mortality was 14%. Conclusions: Complete surgical resection remains the mainstay of therapy and can be curative, but carries a significant risk of intraoperative bleeding and usually requires cardiopulmonary bypass and often complex resection techniques, including cardiac autotransplantation.
UR - http://www.scopus.com/inward/record.url?scp=84861646026&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84861646026&partnerID=8YFLogxK
U2 - 10.1016/j.athoracsur.2012.02.040
DO - 10.1016/j.athoracsur.2012.02.040
M3 - Article
C2 - 22537533
AN - SCOPUS:84861646026
VL - 93
SP - 1972
EP - 1976
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 6
ER -