Contemporary 2-year outcomes of complex gastroschisis

Sherif Emil, Noah Canvasser, Tiffany Chen, Esther Friedrich, Wendy Su

Research output: Contribution to journalArticle

37 Citations (Scopus)

Abstract

Purpose: Outcomes of gastroschisis are influenced by associated intestinal complications. We present a detailed analysis of complex gastroschisis. Methods: A retrospective study of all patients with gastroschisis treated at 2 university neonatal intensive care units between January 1, 2001, and March 31, 2007, was performed. Results: Of 83 patients, 19 (23%) had complex gastroschisis, including atresias (68%), gangrene (37%), closing gastroschisis (32%), perforation (21%), strictures (21%), and volvulus (11%). Prenatal ultrasound did not predict complications. Fifty-three percent underwent primary closure. Duration of mechanical ventilation and total parenteral nutrition (TPN) was 14.4 ± 1.9 days and 90.7 ± 9.0 days, respectively. Enteral feeds started at 35.9 ± 4.6 days. Hospital stay was 104.4 ± 9.6 days. Patients underwent a median of 3 abdominal procedures (range, 2-5) before discharge. Ninety-five percent survived to discharge; 33% and 67% were discharged on TPN and gastrostomy feeds, respectively. Two-year survival was 89%, with 82% on full oral feeding, 12% on a combination of oral and gastrostomy feeding, and 1 patient (who received a liver/bowel transplant) on a combination of enteral and parenteral nutrition. Conclusions: Complex gastroschisis continues to produce significant morbidity. However, most of the patients are TPN free by 2 years of age.

Original languageEnglish (US)
Pages (from-to)1521-1528
Number of pages8
JournalJournal of Pediatric Surgery
Volume47
Issue number8
DOIs
StatePublished - Aug 1 2012
Externally publishedYes

Fingerprint

Gastroschisis
Total Parenteral Nutrition
Gastrostomy
Intestinal Volvulus
Gangrene
Neonatal Intensive Care Units
Parenteral Nutrition
Enteral Nutrition
Artificial Respiration
Small Intestine
Length of Stay
Pathologic Constriction
Retrospective Studies
Morbidity
Transplants
Survival
Liver

Keywords

  • Atresia
  • Complex
  • Gastroschisis
  • Morbidity
  • Mortality
  • Outcomes

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health

Cite this

Contemporary 2-year outcomes of complex gastroschisis. / Emil, Sherif; Canvasser, Noah; Chen, Tiffany; Friedrich, Esther; Su, Wendy.

In: Journal of Pediatric Surgery, Vol. 47, No. 8, 01.08.2012, p. 1521-1528.

Research output: Contribution to journalArticle

Emil, Sherif ; Canvasser, Noah ; Chen, Tiffany ; Friedrich, Esther ; Su, Wendy. / Contemporary 2-year outcomes of complex gastroschisis. In: Journal of Pediatric Surgery. 2012 ; Vol. 47, No. 8. pp. 1521-1528.
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