An oxetane ring can be constructed from 5α-acyloxy-Δ 4(20)-taxoids with osmylation as the first step in the usual manner. The innovation reported here is the use of an intramolecularly available acyl group for the protection of 20-OH by an unexpected 5-to 20-migration under slightly basic conditions.
|Original language||English (US)|
|Number of pages||2|
|Journal||Chinese Chemical Letters|
|State||Published - 1997|
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