Abstract
Helicobacter mustelae infects the ferret stomach and provides an opportunity to study pathogenic determinants of a Helicobacter species in its natural host. We constructed an isogenic urease-negative mutant of H. mustelae which produced no detectable urease and showed a reduced acid tolerance. This mutant provides an opportunity to further evaluate the role of urease in the pathogenesis of Helicobacter infection.
Original language | English (US) |
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Pages (from-to) | 3718-3721 |
Number of pages | 4 |
Journal | Infection and Immunity |
Volume | 63 |
Issue number | 9 |
State | Published - 1995 |
ASJC Scopus subject areas
- Immunology