Abstract
Helicobacter mustelae infects the ferret stomach and provides an opportunity to study pathogenic determinants of a Helicobacter species in its natural host. We constructed an isogenic urease-negative mutant of H. mustelae which produced no detectable urease and showed a reduced acid tolerance. This mutant provides an opportunity to further evaluate the role of urease in the pathogenesis of Helicobacter infection.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 3718-3721 |
| Number of pages | 4 |
| Journal | Infection and Immunity |
| Volume | 63 |
| Issue number | 9 |
| State | Published - 1995 |
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ASJC Scopus subject areas
- Immunology
Cite this
Solnick, J. V., Josenhans, C., Suerbaum, S., Tompkins, L. S., & Labigne, A. (1995). Construction and characterization of an isogenic urease-negative mutant of Helicobacter mustelae. Infection and Immunity, 63(9), 3718-3721.