Consequences of petrochemical ingestion and stress on the immune system of seabirds

Kenneth T. Briggs, M. Eric Gershwin, Daniel W. Anderson

Research output: Contribution to journalArticle

43 Citations (Scopus)

Abstract

The immune system is a target of toxicants and there is increasing awareness of the role of environmental pollutants in altering immune function. Immune suppression may constitute a previously unappreciated source of both acute and chronic impacts on seabirds affected by spilled oil. Thus, it is important to determine (a) if immunosuppression occurs, (b) its importance compared to other mechanisms of impact, (c) its timing and chronicity relative to oil ingestion and post-spill cleaning efforts, and (d) if something can, and should be, done to mitigate its effects. The published evidence concerning immune suppression among oiled seabirds is incomplete and much of it is indirect. Among oiled birds, leukocyte numbers (especially lymphocytes) are depressed in the circulation and the major lymphoid organs (spleen and bursa of Fabricius). At the same time, bone marrow hypercellularity, with an emphasis on erythropoiesis, suggests an adaptive shift from white cell to red cell production in response to haemolytic anaemia. Secondary fungal and bacterial infections, common among seabirds in rehabilitation centres, emphasize the immunosuppressive qualities of petrochemicals. Furthermore, inflammation of the gastrointestinal tract following oil ingestion leads to malabsorption of nutrients (which is immunosuppressive), damage to mucosal immune defences, and impairment of responses to certain antigens, such as those of foods. Unfortunately, direct challenge by viral or bacterial pathogens has been incorporated into very few relevant, laboratory studies: compared with experimental controls, domestic birds fed petroleum distillates and/or oil-emulsifying agents suffer greater mortality, and have depressed ability to kill or phagocytize bacterial pathogens. Cell-mediated immune mechanisms are more sensitive to the toxic effects of petrochemical ingestion than are mechanisms related to antibody production. Petrochemical ingestion produces abnormal concentrations or accelerated metabolism of adrenal corticosteroids. The same is true for birds subjected to handling stress, such as occurs during experimentation with wild birds, and during cleaning of oil-soaked birds. Corticosteroid hormones affect the immune system in many ways, including changes in numbers, and depression of function among lymphocytes. Results of the few recent studies of birds released from cleaning facilities are consistent with the notion of chronic, toxic, or immune system problems. These birds suffer higher than expected mortality rates, disappear from expected breeding and dispersal areas, and generally fail to breed for one or more years. Better long-term success might be obtained with improved assessment of immune function during captivity, and with the use of non-specific potentiators of immune function.

Original languageEnglish (US)
Pages (from-to)718-725
Number of pages8
JournalICES Journal of Marine Science
Volume54
Issue number4
DOIs
StatePublished - 1997

Fingerprint

petrochemicals
immune system
seabird
seabirds
ingestion
bird
birds
oils
cleaning
immunosuppressive agents
oil
adrenal cortex hormones
lymphocytes
distillates
pathogen
erythropoiesis
hemolytic anemia
handling stress
bursa of Fabricius
malabsorption

Keywords

  • Immune system
  • Petroleum ingestion
  • Seabirds
  • Stress effects

ASJC Scopus subject areas

  • Aquatic Science
  • Oceanography

Cite this

Consequences of petrochemical ingestion and stress on the immune system of seabirds. / Briggs, Kenneth T.; Gershwin, M. Eric; Anderson, Daniel W.

In: ICES Journal of Marine Science, Vol. 54, No. 4, 1997, p. 718-725.

Research output: Contribution to journalArticle

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