Connexin36 forms synapses essential for night vision

Jonathan B. Demb; Edward N Pugh Jr

doi:10.1016/S0896-6273(02)01062-0

Connexin36 forms synapses essential for night vision

Jonathan B. Demb, Edward N Pugh Jr

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Rod signals reach ganglion cells via at least five pathways. A new study in this issue of Neuron shows that all pathways from rods to ON-type ganglion cells require connexin36. This is the first physiological demonstration in mammals that a well-defined neural circuit requires a gap junction as an obligatory transmission step.

Original language	English (US)
Pages (from-to)	551-553
Number of pages	3
Journal	Neuron
Volume	36
Issue number	4
DOIs	https://doi.org/10.1016/S0896-6273(02)01062-0
State	Published - Nov 14 2002
Externally published	Yes

ASJC Scopus subject areas

Neuroscience(all)

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10.1016/S0896-6273(02)01062-0

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abstract = "Rod signals reach ganglion cells via at least five pathways. A new study in this issue of Neuron shows that all pathways from rods to ON-type ganglion cells require connexin36. This is the first physiological demonstration in mammals that a well-defined neural circuit requires a gap junction as an obligatory transmission step.",

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