Congenital intradural melanoma surrounding the spinal cord of a nine-day-old Saanen goat

Research output: Contribution to journalArticle

Abstract

A nine-day-old Saanen kid presented for progressive hind limb paresis since birth. Euthanasia was elected, and on postmortem examination a large, pigmented mass was present in the vertebral canal surrounding the lumbosacral and caudal thoracic spinal cord. Histopathology revealed a homogeneous population of round to spindle neoplastic cells containing finely granular pigment consistent with a melanoma. This diagnosis was further supported by a Fontana-Masson stain and immunohistochemistry for PNL2, MelanA and SOX10. The tumour presumably arose from melanocytes or melanocytic precursors within the meninges of the lumbosacral spinal cord. No evidence of neoplasia was seen elsewhere in the body; therefore, the meningeal melanoma likely represents the primary tumour. Goats develop neoplasms less frequently than other species, and reports of congenital tumours in goats are rare.

Original languageEnglish (US)
Article numbere001117
JournalVeterinary Record Case Reports
Volume8
Issue number2
DOIs
StatePublished - Apr 8 2020

Keywords

  • central nervous system (CNS)
  • goats
  • histopathology
  • neonatal disease
  • neoplasia
  • pathology

ASJC Scopus subject areas

  • veterinary(all)

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