Abstract
The clinical course and histologic findings are presented of an infant with an unusual form of pulmonary dysplasia. Characteristic sonographic findings and progressive hypoxemia led to the diagnosis of persistence of the fetal circulation. The patient expired despite ventilatory and pharmacologic intervention. Postmortem findings of severe pulmonary capillary hypoplasia, despite normal anatomical and biochemical parenchymal maturation, were observed. It is suggested that factors controlling pulmonary capillary maturation may be significantly different from those involved in airway and pulmonary parenchymal development..
| Original language | English (US) |
|---|---|
| Pages (from-to) | 299-306 |
| Number of pages | 8 |
| Journal | Fetal and Pediatric Pathology |
| Volume | 3 |
| Issue number | 2-4 |
| DOIs | |
| State | Published - 1985 |
| Externally published | Yes |
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Keywords
- Alveolar capillary dysplasia
- lung
- Persistent fetal circulation
- Vascular anomaly
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Pediatrics, Perinatology, and Child Health
Cite this
Congenital alveolar capillary dysplasia : A developmental vascular anomaly causing persistent pulmonary hypertension of the newborn. / Khorsand, Jila; Tennant, Robert; Gillies, Concettina; Philipps, Anthony F.
In: Fetal and Pediatric Pathology, Vol. 3, No. 2-4, 1985, p. 299-306.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Congenital alveolar capillary dysplasia
T2 - A developmental vascular anomaly causing persistent pulmonary hypertension of the newborn
AU - Khorsand, Jila
AU - Tennant, Robert
AU - Gillies, Concettina
AU - Philipps, Anthony F
PY - 1985
Y1 - 1985
N2 - The clinical course and histologic findings are presented of an infant with an unusual form of pulmonary dysplasia. Characteristic sonographic findings and progressive hypoxemia led to the diagnosis of persistence of the fetal circulation. The patient expired despite ventilatory and pharmacologic intervention. Postmortem findings of severe pulmonary capillary hypoplasia, despite normal anatomical and biochemical parenchymal maturation, were observed. It is suggested that factors controlling pulmonary capillary maturation may be significantly different from those involved in airway and pulmonary parenchymal development..
AB - The clinical course and histologic findings are presented of an infant with an unusual form of pulmonary dysplasia. Characteristic sonographic findings and progressive hypoxemia led to the diagnosis of persistence of the fetal circulation. The patient expired despite ventilatory and pharmacologic intervention. Postmortem findings of severe pulmonary capillary hypoplasia, despite normal anatomical and biochemical parenchymal maturation, were observed. It is suggested that factors controlling pulmonary capillary maturation may be significantly different from those involved in airway and pulmonary parenchymal development..
KW - Alveolar capillary dysplasia
KW - lung
KW - Persistent fetal circulation
KW - Vascular anomaly
UR - http://www.scopus.com/inward/record.url?scp=0022337074&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0022337074&partnerID=8YFLogxK
U2 - 10.3109/15513818509078790
DO - 10.3109/15513818509078790
M3 - Article
C2 - 4095026
AN - SCOPUS:0022337074
VL - 3
SP - 299
EP - 306
JO - Fetal and Pediatric Pathology
JF - Fetal and Pediatric Pathology
SN - 1551-3815
IS - 2-4
ER -