Conformation takes precedence over sequence in adeno-associated virus DNA replication

Rance B Lefebvre, S. Riva, K. I. Berns

Research output: Contribution to journalArticlepeer-review

33 Scopus citations

Abstract

Deletion of an 11-base symmetrical sequence in the inverted terminal repetition of the adeno-associated virus 2 genome inhibits DNA replication. Substitution of either an 8- or a 12-base symmetrical sequence unrelated to the original 11-base sequence restores DNA replication.

Original languageEnglish (US)
Pages (from-to)1416-1419
Number of pages4
JournalMolecular and Cellular Biology
Volume4
Issue number7
StatePublished - 1984
Externally publishedYes

ASJC Scopus subject areas

  • Cell Biology
  • Genetics
  • Molecular Biology

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