Conceptual design of a compact positron tomograph for prostate imaging

J. S. Huber, S. E. Derenzo, J. Qi, W. W. Moses, R. H. Huesman, T. F. Budinger

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We present a conceptual design of a compact positron tomograph for prostate imaging, using a pair of external curved detector banks placed above and below the patient. The lower detector bank is fixed below the patient bed, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 HR+ PET block detectors, forming two arcs (44 cm minor, ∼60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point towards the prostate to minimize resolution degradation in that region. Inter-plane septa extend ∼5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility to detect a spherical tumor of 2.5 cm diameter with a tumor to background of 2:1, requiring a number of counts that should be achievable with a 2 minute scan after a 10 mCi injection (e.g. carbon-11 choline).

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium and Medical Imaging Conference
EditorsD. Merelli, J. Surget, M. Ulma
Volume3
StatePublished - 2000
Externally publishedYes
Event2000 IEEE Nuclear Science Symposium Conference Record - Lyon, France
Duration: Oct 15 2000Oct 20 2000

Other

Other2000 IEEE Nuclear Science Symposium Conference Record
CountryFrance
CityLyon
Period10/15/0010/20/00

Fingerprint

Positrons
Conceptual design
Detectors
Imaging techniques
Tumors
Phosphors
Sampling
Degradation
Crystals
Carbon
Costs

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Huber, J. S., Derenzo, S. E., Qi, J., Moses, W. W., Huesman, R. H., & Budinger, T. F. (2000). Conceptual design of a compact positron tomograph for prostate imaging. In D. Merelli, J. Surget, & M. Ulma (Eds.), IEEE Nuclear Science Symposium and Medical Imaging Conference (Vol. 3)

Conceptual design of a compact positron tomograph for prostate imaging. / Huber, J. S.; Derenzo, S. E.; Qi, J.; Moses, W. W.; Huesman, R. H.; Budinger, T. F.

IEEE Nuclear Science Symposium and Medical Imaging Conference. ed. / D. Merelli; J. Surget; M. Ulma. Vol. 3 2000.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Huber, JS, Derenzo, SE, Qi, J, Moses, WW, Huesman, RH & Budinger, TF 2000, Conceptual design of a compact positron tomograph for prostate imaging. in D Merelli, J Surget & M Ulma (eds), IEEE Nuclear Science Symposium and Medical Imaging Conference. vol. 3, 2000 IEEE Nuclear Science Symposium Conference Record, Lyon, France, 10/15/00.
Huber JS, Derenzo SE, Qi J, Moses WW, Huesman RH, Budinger TF. Conceptual design of a compact positron tomograph for prostate imaging. In Merelli D, Surget J, Ulma M, editors, IEEE Nuclear Science Symposium and Medical Imaging Conference. Vol. 3. 2000
Huber, J. S. ; Derenzo, S. E. ; Qi, J. ; Moses, W. W. ; Huesman, R. H. ; Budinger, T. F. / Conceptual design of a compact positron tomograph for prostate imaging. IEEE Nuclear Science Symposium and Medical Imaging Conference. editor / D. Merelli ; J. Surget ; M. Ulma. Vol. 3 2000.
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