Conceptual design of a compact positron tomograph for prostate imaging

J. S. Huber, S. E. Derenzo, J. Qi, W. W. Moses, R. H. Huesman, T. F. Budinger

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bend, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine).

Original languageEnglish (US)
Pages (from-to)1506-1511
Number of pages6
JournalIEEE Transactions on Nuclear Science
Volume48
Issue number4 II
DOIs
StatePublished - Aug 2001
Externally publishedYes

Fingerprint

Positrons
Conceptual design
positrons
Detectors
Imaging techniques
detectors
Tumors
tumors
septum
choline
sensitivity
Fluorine
Phosphors
scintillation counters
fluorine
arcs
attenuation
sampling
injection
degradation

Keywords

  • Biomedical imaging
  • Positron emission tomography

ASJC Scopus subject areas

  • Electrical and Electronic Engineering
  • Nuclear Energy and Engineering

Cite this

Huber, J. S., Derenzo, S. E., Qi, J., Moses, W. W., Huesman, R. H., & Budinger, T. F. (2001). Conceptual design of a compact positron tomograph for prostate imaging. IEEE Transactions on Nuclear Science, 48(4 II), 1506-1511. https://doi.org/10.1109/23.958388

Conceptual design of a compact positron tomograph for prostate imaging. / Huber, J. S.; Derenzo, S. E.; Qi, J.; Moses, W. W.; Huesman, R. H.; Budinger, T. F.

In: IEEE Transactions on Nuclear Science, Vol. 48, No. 4 II, 08.2001, p. 1506-1511.

Research output: Contribution to journalArticle

Huber, JS, Derenzo, SE, Qi, J, Moses, WW, Huesman, RH & Budinger, TF 2001, 'Conceptual design of a compact positron tomograph for prostate imaging', IEEE Transactions on Nuclear Science, vol. 48, no. 4 II, pp. 1506-1511. https://doi.org/10.1109/23.958388
Huber JS, Derenzo SE, Qi J, Moses WW, Huesman RH, Budinger TF. Conceptual design of a compact positron tomograph for prostate imaging. IEEE Transactions on Nuclear Science. 2001 Aug;48(4 II):1506-1511. https://doi.org/10.1109/23.958388
Huber, J. S. ; Derenzo, S. E. ; Qi, J. ; Moses, W. W. ; Huesman, R. H. ; Budinger, T. F. / Conceptual design of a compact positron tomograph for prostate imaging. In: IEEE Transactions on Nuclear Science. 2001 ; Vol. 48, No. 4 II. pp. 1506-1511.
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