Abstract
We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bend, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine).
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1506-1511 |
| Number of pages | 6 |
| Journal | IEEE Transactions on Nuclear Science |
| Volume | 48 |
| Issue number | 4 II |
| DOIs | |
| State | Published - Aug 2001 |
| Externally published | Yes |
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Keywords
- Biomedical imaging
- Positron emission tomography
ASJC Scopus subject areas
- Electrical and Electronic Engineering
- Nuclear Energy and Engineering
Cite this
Conceptual design of a compact positron tomograph for prostate imaging. / Huber, J. S.; Derenzo, S. E.; Qi, J.; Moses, W. W.; Huesman, R. H.; Budinger, T. F.
In: IEEE Transactions on Nuclear Science, Vol. 48, No. 4 II, 08.2001, p. 1506-1511.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Conceptual design of a compact positron tomograph for prostate imaging
AU - Huber, J. S.
AU - Derenzo, S. E.
AU - Qi, J.
AU - Moses, W. W.
AU - Huesman, R. H.
AU - Budinger, T. F.
PY - 2001/8
Y1 - 2001/8
N2 - We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bend, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine).
AB - We present a conceptual design of a compact positron tomograph for prostate imaging using a pair of external curved detector banks, one placed above and one below the patient. The lower detector bank is fixed below the patient bend, and the top bank adjusts vertically for maximum sensitivity and patient access. Each bank is composed of 40 conventional block detectors, forming two arcs (44 cm minor, 60 cm major axis) that are tilted to minimize attenuation and positioned as close as possible to the patient to improve sensitivity. The individual detectors are angled to point toward the prostate to minimize resolution degradation in that region. Interplane septa extend 5 cm beyond the scintillator crystals to reduce random and scatter backgrounds. A patient is not fully encircled by detector rings in order to minimize cost, causing incomplete sampling due to the side gaps. Monte Carlo simulation (including randoms and scatter) demonstrates the feasibility of detecting and differentiating partial and whole prostate tumors with a tumor-to-background ratio of 2:1, utilizing the number of events that should be achievable with a 6-min scan after a10 mCi injection (e.g., carbon-11 choline or fluorine-18 fluorocholine).
KW - Biomedical imaging
KW - Positron emission tomography
UR - http://www.scopus.com/inward/record.url?scp=0035428583&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0035428583&partnerID=8YFLogxK
U2 - 10.1109/23.958388
DO - 10.1109/23.958388
M3 - Article
AN - SCOPUS:0035428583
VL - 48
SP - 1506
EP - 1511
JO - IEEE Transactions on Nuclear Science
JF - IEEE Transactions on Nuclear Science
SN - 0018-9499
IS - 4 II
ER -