Abstract
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis that can lead to decreased health-related quality of life and permanent joint damage leading to functional decline. In addition to joint and skin manifestations, both psoriasis and PsA are associated with numerous comorbidities and extraarticular/cutaneous manifestations, which may influence the physician's choice of therapy. The objectives of this review are (1) to identify comorbidities in patients with PsA based on the available evidence; (2) to examine the effects of these comorbidities or extraarticular/cutaneous manifestation on the management of patients with PsA as well as the selection of therapy; and (3) to highlight research needs around comorbidities and treatment paradigms. This review is part of a treatment recommendations update initiated by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).
Original language | English (US) |
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Pages (from-to) | 2315-2322 |
Number of pages | 8 |
Journal | Journal of Rheumatology |
Volume | 41 |
Issue number | 11 |
DOIs | |
State | Published - Nov 1 2014 |
Keywords
- Autoimmune ophthalmic disease
- Cardiovascular
- Diabetes
- Disease obesity
- Metabolic syndrome
- Osteoporosis
ASJC Scopus subject areas
- Rheumatology
- Immunology
- Immunology and Allergy