Comprehensive treatment of psoriatic arthritis: Managing comorbidities and extraarticular manifestations

Alexis Ogdie, Sergio Schwartzman, Lihi Eder, Ajesh B. Maharaj, Devy Zisman, Siba P Raychaudhuri, Soumya M. Reddy, Elaine Husni

Research output: Contribution to journalArticle

35 Scopus citations

Abstract

Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis that can lead to decreased health-related quality of life and permanent joint damage leading to functional decline. In addition to joint and skin manifestations, both psoriasis and PsA are associated with numerous comorbidities and extraarticular/cutaneous manifestations, which may influence the physician's choice of therapy. The objectives of this review are (1) to identify comorbidities in patients with PsA based on the available evidence; (2) to examine the effects of these comorbidities or extraarticular/cutaneous manifestation on the management of patients with PsA as well as the selection of therapy; and (3) to highlight research needs around comorbidities and treatment paradigms. This review is part of a treatment recommendations update initiated by the Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA).

Original languageEnglish (US)
Pages (from-to)2315-2322
Number of pages8
JournalJournal of Rheumatology
Volume41
Issue number11
DOIs
StatePublished - Nov 1 2014

Keywords

  • Autoimmune ophthalmic disease
  • Cardiovascular
  • Diabetes
  • Disease obesity
  • Metabolic syndrome
  • Osteoporosis

ASJC Scopus subject areas

  • Rheumatology
  • Immunology
  • Immunology and Allergy

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