Comprehensive assessment of the slice sensitivity profiles in breast tomosynthesis and breast CT

Anita Nosratieh, Kai Yang, Shadi Aminololama-Shakeri, John M Boone

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Purpose: This study experimentally evaluated the slice sensitivity profile (SSP) and its relationship between acquisition angle, object size, and cone angle. The sensitivity profile metric was used to characterize a breast tomosynthesis systems resolution in the z-axis. The SSP was also measured on a prototype breast computed tomography (bCT) system. Methods: The SSP was measured using brass disks placed within adipose tissue-equivalent breast phantoms. The digital tomosynthesis system (Selenia Dimensions, Hologic Corporation, Bedford, MA) acquires projection images over a 15° angular range and the bCT scanner acquires projection images over a 360° angular range. Angular ranges between 15° and 360° were studied by using a subset of the projection images acquired on the bCT scanner. The SSP was determined by measuring a background-corrected mean gray scale value as a function of the z-position (axis normal to the plane of the detector). Results: The results show that SSP improves when the angular acquisition range is increased and the SSP approaches a delta function for angles greater than 180°. Smaller objects have a narrower SSP and the SSP is not significantly dependent on the cone angle. For a 2.5, 5, 10 mm disk, the full width at half maximum of the SSP was 35, 61, 115 mm, respectively, on the tomosynthesis system (at 15°) and was 0.5 mm for all disk diameters on the bCT scanner (at 360°). Conclusions: The SSP is dependent on object size and angular acquisition range. These dependencies are overcome once the angular acquisition range is increased beyond 180°.

Original languageEnglish (US)
Pages (from-to)7254-7261
Number of pages8
JournalMedical Physics
Volume39
Issue number12
DOIs
StatePublished - Dec 2012

Fingerprint

Breast
X-Ray Computed Tomography Scanners
Selenium
Adipose Tissue
Tomography

Keywords

  • breast imaging
  • image quality
  • tomosynthesis

ASJC Scopus subject areas

  • Biophysics
  • Radiology Nuclear Medicine and imaging

Cite this

Comprehensive assessment of the slice sensitivity profiles in breast tomosynthesis and breast CT. / Nosratieh, Anita; Yang, Kai; Aminololama-Shakeri, Shadi; Boone, John M.

In: Medical Physics, Vol. 39, No. 12, 12.2012, p. 7254-7261.

Research output: Contribution to journalArticle

@article{c51e7a79a0534369bd0fc5672dc2e490,
title = "Comprehensive assessment of the slice sensitivity profiles in breast tomosynthesis and breast CT",
abstract = "Purpose: This study experimentally evaluated the slice sensitivity profile (SSP) and its relationship between acquisition angle, object size, and cone angle. The sensitivity profile metric was used to characterize a breast tomosynthesis systems resolution in the z-axis. The SSP was also measured on a prototype breast computed tomography (bCT) system. Methods: The SSP was measured using brass disks placed within adipose tissue-equivalent breast phantoms. The digital tomosynthesis system (Selenia Dimensions, Hologic Corporation, Bedford, MA) acquires projection images over a 15° angular range and the bCT scanner acquires projection images over a 360° angular range. Angular ranges between 15° and 360° were studied by using a subset of the projection images acquired on the bCT scanner. The SSP was determined by measuring a background-corrected mean gray scale value as a function of the z-position (axis normal to the plane of the detector). Results: The results show that SSP improves when the angular acquisition range is increased and the SSP approaches a delta function for angles greater than 180°. Smaller objects have a narrower SSP and the SSP is not significantly dependent on the cone angle. For a 2.5, 5, 10 mm disk, the full width at half maximum of the SSP was 35, 61, 115 mm, respectively, on the tomosynthesis system (at 15°) and was 0.5 mm for all disk diameters on the bCT scanner (at 360°). Conclusions: The SSP is dependent on object size and angular acquisition range. These dependencies are overcome once the angular acquisition range is increased beyond 180°.",
keywords = "breast imaging, image quality, tomosynthesis",
author = "Anita Nosratieh and Kai Yang and Shadi Aminololama-Shakeri and Boone, {John M}",
year = "2012",
month = "12",
doi = "10.1118/1.4764908",
language = "English (US)",
volume = "39",
pages = "7254--7261",
journal = "Medical Physics",
issn = "0094-2405",
publisher = "AAPM - American Association of Physicists in Medicine",
number = "12",

}

TY - JOUR

T1 - Comprehensive assessment of the slice sensitivity profiles in breast tomosynthesis and breast CT

AU - Nosratieh, Anita

AU - Yang, Kai

AU - Aminololama-Shakeri, Shadi

AU - Boone, John M

PY - 2012/12

Y1 - 2012/12

N2 - Purpose: This study experimentally evaluated the slice sensitivity profile (SSP) and its relationship between acquisition angle, object size, and cone angle. The sensitivity profile metric was used to characterize a breast tomosynthesis systems resolution in the z-axis. The SSP was also measured on a prototype breast computed tomography (bCT) system. Methods: The SSP was measured using brass disks placed within adipose tissue-equivalent breast phantoms. The digital tomosynthesis system (Selenia Dimensions, Hologic Corporation, Bedford, MA) acquires projection images over a 15° angular range and the bCT scanner acquires projection images over a 360° angular range. Angular ranges between 15° and 360° were studied by using a subset of the projection images acquired on the bCT scanner. The SSP was determined by measuring a background-corrected mean gray scale value as a function of the z-position (axis normal to the plane of the detector). Results: The results show that SSP improves when the angular acquisition range is increased and the SSP approaches a delta function for angles greater than 180°. Smaller objects have a narrower SSP and the SSP is not significantly dependent on the cone angle. For a 2.5, 5, 10 mm disk, the full width at half maximum of the SSP was 35, 61, 115 mm, respectively, on the tomosynthesis system (at 15°) and was 0.5 mm for all disk diameters on the bCT scanner (at 360°). Conclusions: The SSP is dependent on object size and angular acquisition range. These dependencies are overcome once the angular acquisition range is increased beyond 180°.

AB - Purpose: This study experimentally evaluated the slice sensitivity profile (SSP) and its relationship between acquisition angle, object size, and cone angle. The sensitivity profile metric was used to characterize a breast tomosynthesis systems resolution in the z-axis. The SSP was also measured on a prototype breast computed tomography (bCT) system. Methods: The SSP was measured using brass disks placed within adipose tissue-equivalent breast phantoms. The digital tomosynthesis system (Selenia Dimensions, Hologic Corporation, Bedford, MA) acquires projection images over a 15° angular range and the bCT scanner acquires projection images over a 360° angular range. Angular ranges between 15° and 360° were studied by using a subset of the projection images acquired on the bCT scanner. The SSP was determined by measuring a background-corrected mean gray scale value as a function of the z-position (axis normal to the plane of the detector). Results: The results show that SSP improves when the angular acquisition range is increased and the SSP approaches a delta function for angles greater than 180°. Smaller objects have a narrower SSP and the SSP is not significantly dependent on the cone angle. For a 2.5, 5, 10 mm disk, the full width at half maximum of the SSP was 35, 61, 115 mm, respectively, on the tomosynthesis system (at 15°) and was 0.5 mm for all disk diameters on the bCT scanner (at 360°). Conclusions: The SSP is dependent on object size and angular acquisition range. These dependencies are overcome once the angular acquisition range is increased beyond 180°.

KW - breast imaging

KW - image quality

KW - tomosynthesis

UR - http://www.scopus.com/inward/record.url?scp=84870948675&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84870948675&partnerID=8YFLogxK

U2 - 10.1118/1.4764908

DO - 10.1118/1.4764908

M3 - Article

C2 - 23231276

AN - SCOPUS:84870948675

VL - 39

SP - 7254

EP - 7261

JO - Medical Physics

JF - Medical Physics

SN - 0094-2405

IS - 12

ER -