Comprehensive annotation of mature peptides and genotypes for Zika Virus

Guangyu Sun, Christopher N. Larsen, Nicole Baumgarth, Edward B. Klem, Richard H. Scheuermann

Research output: Contribution to journalArticlepeer-review

15 Scopus citations

Abstract

The rapid spread of Zika virus (ZIKV) has caused much concern in the global health community, due in part to a link to fetal microcephaly and other neurological illnesses. While an increasing amount of ZIKV genomic sequence data is being generated, an understanding of the virus molecular biology is still greatly lacking. A significant step towards establishing ZIKV proteomics would be the compilation of all proteins produced by the virus, and the resultant virus genotypes. Here we report for the first time such data, using new computational methods for the annotation of mature peptide proteins, genotypes, and recombination events for all ZIKV genomes. The data is made publicly available through the Virus Pathogen Resource at www.viprbrc.org.

Original languageEnglish (US)
Article numbere0170462
JournalPLoS One
Volume12
Issue number1
DOIs
StatePublished - Jan 1 2017

ASJC Scopus subject areas

  • Medicine(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Agricultural and Biological Sciences(all)

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