Abstract
1. 1. The acidic and neutral glycoproteins secreted by cultured tracheal explants from pigs, sheep, rats, mice, monkeys, guinea pigs, dogs and chickens were purified and fractionated by column chromatography on DEAE-cellulose and by electrophoresis on cellulose acetate. 2. 2. The ratios of acidic to neutral mucus glycoproteins were compared for the above animais with that of mucus glycoproteins secreted by cultured human bronchi. 3. 3. The observed ratios of acidic to neutral glycoproteins ranged from 4.0 (mouse) to 7.2 (chicken and pig) from cultured tracheae; secreted human bronchial mucus had a ratio of 2.7. 4. 4. The ratio of acidic to neutral glycoproteins secreted by tracheal explants varied with duration of incubation of the trachea in culture.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 195-200 |
| Number of pages | 6 |
| Journal | Comparative Biochemistry and Physiology -- Part B: Biochemistry and |
| Volume | 62 |
| Issue number | 3 |
| DOIs | |
| State | Published - 1979 |
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Composition of glycoproteins secreted by tracheal explants from various animal species. / Kaizu, Tokio; Lyons, Sheila A.; Cross, Carroll E; Jennings, Mark D.; Last, Jerold A.
In: Comparative Biochemistry and Physiology -- Part B: Biochemistry and, Vol. 62, No. 3, 1979, p. 195-200.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Composition of glycoproteins secreted by tracheal explants from various animal species
AU - Kaizu, Tokio
AU - Lyons, Sheila A.
AU - Cross, Carroll E
AU - Jennings, Mark D.
AU - Last, Jerold A
PY - 1979
Y1 - 1979
N2 - 1. 1. The acidic and neutral glycoproteins secreted by cultured tracheal explants from pigs, sheep, rats, mice, monkeys, guinea pigs, dogs and chickens were purified and fractionated by column chromatography on DEAE-cellulose and by electrophoresis on cellulose acetate. 2. 2. The ratios of acidic to neutral mucus glycoproteins were compared for the above animais with that of mucus glycoproteins secreted by cultured human bronchi. 3. 3. The observed ratios of acidic to neutral glycoproteins ranged from 4.0 (mouse) to 7.2 (chicken and pig) from cultured tracheae; secreted human bronchial mucus had a ratio of 2.7. 4. 4. The ratio of acidic to neutral glycoproteins secreted by tracheal explants varied with duration of incubation of the trachea in culture.
AB - 1. 1. The acidic and neutral glycoproteins secreted by cultured tracheal explants from pigs, sheep, rats, mice, monkeys, guinea pigs, dogs and chickens were purified and fractionated by column chromatography on DEAE-cellulose and by electrophoresis on cellulose acetate. 2. 2. The ratios of acidic to neutral mucus glycoproteins were compared for the above animais with that of mucus glycoproteins secreted by cultured human bronchi. 3. 3. The observed ratios of acidic to neutral glycoproteins ranged from 4.0 (mouse) to 7.2 (chicken and pig) from cultured tracheae; secreted human bronchial mucus had a ratio of 2.7. 4. 4. The ratio of acidic to neutral glycoproteins secreted by tracheal explants varied with duration of incubation of the trachea in culture.
UR - http://www.scopus.com/inward/record.url?scp=0018355313&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0018355313&partnerID=8YFLogxK
U2 - 10.1016/0305-0491(79)90199-8
DO - 10.1016/0305-0491(79)90199-8
M3 - Article
C2 - 45551
AN - SCOPUS:0018355313
VL - 62
SP - 195
EP - 200
JO - Comparative biochemistry and physiology. B, Comparative biochemistry
JF - Comparative biochemistry and physiology. B, Comparative biochemistry
SN - 1096-4959
IS - 3
ER -