Despite many improvements over the past three decades, hemodialysis fails to completely restore health in patients who have lost native kidney function, so debate continues about how much dialysis is enough. It is clear that uremic symptoms such as nausea, vomiting, pruritus, mental lethargy, and anorexia can appear in patients who are inadequately dialyzed and are certain to appear if dialysis is omitted. However, even in patients who have none of these overt symptoms, insufficient dialysis has been associated with an increase in the number and duration of hospitalizations and with a shortened life expectancy (1-4). Because these serious complications are potentially preventable, clinicians providing dialysis for patients with end-stage renal disease (ESRD) must have a practical understanding of dialysis adequacy, how to measure it, and the basis for currently acceptable minimum standards. This requires a working familiarity with the theoretical constructs of solute and membrane dynamics, the strategies to improve dialysis efficiency, and the pitfalls inherent in prescribing and supervising dialysis.
|Original language||English (US)|
|Title of host publication||Complications of Dialysis|
|Number of pages||27|
|State||Published - Jan 1 2000|
ASJC Scopus subject areas