Complexity in late-life depression: Impact of confounding factors on diagnosis, treatment, and outcomes

Helen C. Kales, Marcia Valenstein

Research output: Contribution to journalArticle

21 Scopus citations


Late-life depression is a heterogeneous syndrome. Although depression in elderly patients is highly treatable, a number of factors or confounds create complexity in its overall management. Patient factors, such as medical illness, neuropsychiatric comorbidity, and race, may interact with provider factors to make management more complex. Outcomes and services research indicate that these factors, particularly medical illness, affect whether late-life depression is appropriately detected, diagnosed, and treated. Attention to such factors must be included in an agenda for mental health services research, with emphasis on the delivery of effective treatment to elderly patients with depression and improved outcomes in clinical settings.

Original languageEnglish (US)
Pages (from-to)147-155
Number of pages9
JournalJournal of Geriatric Psychiatry and Neurology
Issue number3
StatePublished - Jan 1 2002
Externally publishedYes


ASJC Scopus subject areas

  • Clinical Neurology
  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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