Complete genome sequence of Methanothermus fervidus type strain (V24S T)

Iain Anderson, Olivier Duplex Ngatchou Djao, Monica Misra, Olga Chertkov, Matt Nolan, Susan Lucas, Alla Lapidus, Tijana Glavina del Rio, Hope Tice, Jan Fang Cheng, Roxanne Tapia, Cliff Han, Lynne Goodwin, Sam Pitluck, Konstantinos Liolios, Natalia Ivanova, Konstantinos Mavromatis, Natalia Mikhailova, Amrita Pati, Evelyne BrambillaAmy Chen, Krishna Palaniappan, Miriam Land, Loren Hauser, Yun Juan Chang, Cynthia D. Jeffries, Johannes Sikorski, Stefan Spring, Manfred Rohde, Konrad Eichinger, Harald Huber, Reinhard Wirth, Markus Göker, John C. Detter, Tanja Woyke, James Bristow, Jonathan A Eisen, Victor Markowitz, Philip Hugenholtz, Hans Peter Klenk, Nikos C. Kyrpides

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Methanothermus fervidus Stetter 1982 is the type strain of the genus Methanothermus. This hyperthermophilic genus is of a thought to be endemic in Icelandic hot springs. M. fervidus was not only the first characterized organism with a maximal growth temperature (97°C) close to the boiling point of water, but also the first archaeon in which a detailed functional analysis of its histone protein was reported and the first one in which the function of 2,3-cyclodiphosphoglycerate in thermoadaptation was characterized. Strain V24S T is of interest because of its very low substrate ranges, it grows only on H 2 + CO 2. This is the first completed genome sequence of the family Methanothermaceae. Here we describe the features of this organism, together with the complete genome sequence and annotation. The 1,243,342 bp long genome with its 1,311 protein-coding and 50 RNA genes is a part of the Genomic Encyclopedia of Bacteria and Archaea project.

Original languageEnglish (US)
Pages (from-to)315-324
Number of pages10
JournalStandards in Genomic Sciences
Issue number3
StatePublished - 2010


  • Chemolithoautotroph
  • Euryarchaeota
  • GEBA
  • Gram-positive
  • Hyperthermophile
  • Methanothermaceae
  • Motile
  • Strictly anaerobic

ASJC Scopus subject areas

  • Genetics


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