Abstract
In this functional-MRI study we examined the hypothesis that the prefrontal cortex responds differently to the extent of competition during retrieval, whereas the parietal cortex is responsible for problem representation that should not be directly related to the competition. Participants mastered arbitrary person-location pairs, and their recognition memory was tested in a functional-MRI session. The pairs were constructed such that a person was associated with one, two, or three different locations and vice versa. The recognition time increased with the number of associations, reflecting increased competition. A confirmatory analysis of imaging data with prespecified prefrontal and parietal regions showed that, although both regions were highly involved during memory retrieval, only the prefrontal region responded to the levels of competition. This result was consistent with predictions of an information-processing model as well as with an exploratory identification of regions of interest.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 7412-7417 |
| Number of pages | 6 |
| Journal | Proceedings of the National Academy of Sciences of the United States of America |
| Volume | 100 |
| Issue number | 12 |
| DOIs | |
| State | Published - Jun 10 2003 |
| Externally published | Yes |
Fingerprint
ASJC Scopus subject areas
- Genetics
- General
Cite this
Competition and representation during memory retrieval : Roles of the prefrontal cortex and the posterior parietal cortex. / Sohn, Myeong Ho; Goode, Adam; Stenger, V. Andrew; Carter, Cameron S; Anderson, John R.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 100, No. 12, 10.06.2003, p. 7412-7417.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Competition and representation during memory retrieval
T2 - Roles of the prefrontal cortex and the posterior parietal cortex
AU - Sohn, Myeong Ho
AU - Goode, Adam
AU - Stenger, V. Andrew
AU - Carter, Cameron S
AU - Anderson, John R.
PY - 2003/6/10
Y1 - 2003/6/10
N2 - In this functional-MRI study we examined the hypothesis that the prefrontal cortex responds differently to the extent of competition during retrieval, whereas the parietal cortex is responsible for problem representation that should not be directly related to the competition. Participants mastered arbitrary person-location pairs, and their recognition memory was tested in a functional-MRI session. The pairs were constructed such that a person was associated with one, two, or three different locations and vice versa. The recognition time increased with the number of associations, reflecting increased competition. A confirmatory analysis of imaging data with prespecified prefrontal and parietal regions showed that, although both regions were highly involved during memory retrieval, only the prefrontal region responded to the levels of competition. This result was consistent with predictions of an information-processing model as well as with an exploratory identification of regions of interest.
AB - In this functional-MRI study we examined the hypothesis that the prefrontal cortex responds differently to the extent of competition during retrieval, whereas the parietal cortex is responsible for problem representation that should not be directly related to the competition. Participants mastered arbitrary person-location pairs, and their recognition memory was tested in a functional-MRI session. The pairs were constructed such that a person was associated with one, two, or three different locations and vice versa. The recognition time increased with the number of associations, reflecting increased competition. A confirmatory analysis of imaging data with prespecified prefrontal and parietal regions showed that, although both regions were highly involved during memory retrieval, only the prefrontal region responded to the levels of competition. This result was consistent with predictions of an information-processing model as well as with an exploratory identification of regions of interest.
UR - http://www.scopus.com/inward/record.url?scp=0038471165&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0038471165&partnerID=8YFLogxK
U2 - 10.1073/pnas.0832374100
DO - 10.1073/pnas.0832374100
M3 - Article
C2 - 12773617
AN - SCOPUS:0038471165
VL - 100
SP - 7412
EP - 7417
JO - Proceedings of the National Academy of Sciences of the United States of America
JF - Proceedings of the National Academy of Sciences of the United States of America
SN - 0027-8424
IS - 12
ER -