Comparison of statistical reconstructions with isotropic and anisotropic resolution

Jinyi Qi

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Statistical reconstruction methods based on the penalized maximum likelihood (or maximum a posteriori) principle have gained increasing attention in emission tomography. Fessler and Rogers have shown that the penalized maximum likelihood reconstruction with a conventional quadratic penalty results in anisotropic point spread functions (PSFs). Several approaches have been developed to design modified penalty functions to achieve isotropic PSFs. While an image with an Isotropic PSF may be useful in some situations, its performance on clinical detection and quantitation tasks is unknown. In this paper, we compare the task performances using computer simulations. The lesion detectability is measured by a channelized Hotelling observer. The quantitation is evaluated by the bias and variance. The results show that reconstructions with an isotropic PSF may not be suitable for lesion detection and quantitation.

Original languageEnglish (US)
Title of host publicationIEEE Nuclear Science Symposium Conference Record
EditorsJ.A. Seibert
Pages3624-3628
Number of pages5
Volume6
StatePublished - 2004
Event2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors - Rome, Italy
Duration: Oct 16 2004Oct 22 2004

Other

Other2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors
CountryItaly
CityRome
Period10/16/0410/22/04

Fingerprint

Optical transfer function
Maximum likelihood
Tomography
Computer simulation

ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Industrial and Manufacturing Engineering

Cite this

Qi, J. (2004). Comparison of statistical reconstructions with isotropic and anisotropic resolution. In J. A. Seibert (Ed.), IEEE Nuclear Science Symposium Conference Record (Vol. 6, pp. 3624-3628). [M9-291]

Comparison of statistical reconstructions with isotropic and anisotropic resolution. / Qi, Jinyi.

IEEE Nuclear Science Symposium Conference Record. ed. / J.A. Seibert. Vol. 6 2004. p. 3624-3628 M9-291.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Qi, J 2004, Comparison of statistical reconstructions with isotropic and anisotropic resolution. in JA Seibert (ed.), IEEE Nuclear Science Symposium Conference Record. vol. 6, M9-291, pp. 3624-3628, 2004 Nuclear Science Symposium, Medical Imaging Conference, Symposium on Nuclear Power Systems and the 14th International Workshop on Room Temperature Semiconductor X- and Gamma- Ray Detectors, Rome, Italy, 10/16/04.
Qi J. Comparison of statistical reconstructions with isotropic and anisotropic resolution. In Seibert JA, editor, IEEE Nuclear Science Symposium Conference Record. Vol. 6. 2004. p. 3624-3628. M9-291
Qi, Jinyi. / Comparison of statistical reconstructions with isotropic and anisotropic resolution. IEEE Nuclear Science Symposium Conference Record. editor / J.A. Seibert. Vol. 6 2004. pp. 3624-3628
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