Comparison of sampling methods for profiling cervicovaginal microbiome in rhesus macaques

Brian A. Schmidt, Ronald Phillips, Matthew Rolston, Reben Raeman, Smita Iyer

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Cervicovaginal bacteria cause inflammation which in turn increases HIV risk. Profiling the cervicovaginal microbiome, therefore, is instrumental for vaccine development. We show that the microbiome profile captured by cervicovaginal lavage is comparable to samples obtained by vaginal swabs. Thus, lavage may serve as a sampling strategy in NHP vaccine studies.

Original languageEnglish (US)
JournalJournal of Medical Primatology
DOIs
StateAccepted/In press - Jan 1 2018

Keywords

  • 16S rRNA
  • HIV
  • lavage
  • swab

ASJC Scopus subject areas

  • Animal Science and Zoology
  • veterinary(all)

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