Abstract
We sought to compare coagulation test results obtained from patients using 2 plastic blood collection tubes and the traditional glass blood collection tube. Blood specimens were obtained from 241 patients in 3.2% buffered sodium citrate using standard glass tubes, in 3.2% buffered sodium citrate in plastic tubes, and in 3.2% sodium citrate "sandwich" tubes (plastic within plastic). All samples were obtained and processed contemporaneously and tested for prothrombin time (PT) and activated partial thromboplastin time (aPTT). Residual plasma was frozen at -70°C for future testing, including fibrinogen, antithrombin, plasminogen, protein C and protein S (functional and antigenic), dilute Russell viper venom time (DRVVT), ristocetin cofactor, factor XIII, D dimer, anti-Xa activity, and prothrombin fragment. Although paired t test analysis revealed statistically significant differences (P < .05) between glass and plastic for PT, aPTT, fibrinogen, protein C (functional and antigenic), functional protein S, DRVVT and confirmation method, antithrombin, and factor XIII, these differences were not considered clinically significant.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 843-848 |
| Number of pages | 6 |
| Journal | American Journal of Clinical Pathology |
| Volume | 122 |
| Issue number | 6 |
| DOIs | |
| State | Published - Dec 2004 |
Fingerprint
Keywords
- Coagulation testing
- Glass tubes
- Plastic tubes
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Comparison of samples obtained from 3.2% sodium citrate glass and two 3.2% sodium citrate plastic blood collection tubes used in coagulation testing. / Gosselin, Robert C.; Janatpour, Kim; Larkin, Edward C.; Lee, Yanlap P.; Owings, John T.
In: American Journal of Clinical Pathology, Vol. 122, No. 6, 12.2004, p. 843-848.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Comparison of samples obtained from 3.2% sodium citrate glass and two 3.2% sodium citrate plastic blood collection tubes used in coagulation testing
AU - Gosselin, Robert C.
AU - Janatpour, Kim
AU - Larkin, Edward C.
AU - Lee, Yanlap P.
AU - Owings, John T
PY - 2004/12
Y1 - 2004/12
N2 - We sought to compare coagulation test results obtained from patients using 2 plastic blood collection tubes and the traditional glass blood collection tube. Blood specimens were obtained from 241 patients in 3.2% buffered sodium citrate using standard glass tubes, in 3.2% buffered sodium citrate in plastic tubes, and in 3.2% sodium citrate "sandwich" tubes (plastic within plastic). All samples were obtained and processed contemporaneously and tested for prothrombin time (PT) and activated partial thromboplastin time (aPTT). Residual plasma was frozen at -70°C for future testing, including fibrinogen, antithrombin, plasminogen, protein C and protein S (functional and antigenic), dilute Russell viper venom time (DRVVT), ristocetin cofactor, factor XIII, D dimer, anti-Xa activity, and prothrombin fragment. Although paired t test analysis revealed statistically significant differences (P < .05) between glass and plastic for PT, aPTT, fibrinogen, protein C (functional and antigenic), functional protein S, DRVVT and confirmation method, antithrombin, and factor XIII, these differences were not considered clinically significant.
AB - We sought to compare coagulation test results obtained from patients using 2 plastic blood collection tubes and the traditional glass blood collection tube. Blood specimens were obtained from 241 patients in 3.2% buffered sodium citrate using standard glass tubes, in 3.2% buffered sodium citrate in plastic tubes, and in 3.2% sodium citrate "sandwich" tubes (plastic within plastic). All samples were obtained and processed contemporaneously and tested for prothrombin time (PT) and activated partial thromboplastin time (aPTT). Residual plasma was frozen at -70°C for future testing, including fibrinogen, antithrombin, plasminogen, protein C and protein S (functional and antigenic), dilute Russell viper venom time (DRVVT), ristocetin cofactor, factor XIII, D dimer, anti-Xa activity, and prothrombin fragment. Although paired t test analysis revealed statistically significant differences (P < .05) between glass and plastic for PT, aPTT, fibrinogen, protein C (functional and antigenic), functional protein S, DRVVT and confirmation method, antithrombin, and factor XIII, these differences were not considered clinically significant.
KW - Coagulation testing
KW - Glass tubes
KW - Plastic tubes
UR - http://www.scopus.com/inward/record.url?scp=9644279422&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=9644279422&partnerID=8YFLogxK
U2 - 10.1309/7V2K-P1HP-9Q29-BMN2
DO - 10.1309/7V2K-P1HP-9Q29-BMN2
M3 - Article
VL - 122
SP - 843
EP - 848
JO - American Journal of Clinical Pathology
JF - American Journal of Clinical Pathology
SN - 0002-9173
IS - 6
ER -