Comparison of macular thickness measurement and segmentation error rate between stratus and fourier-domain optical coherence tomography

Sara Modjtahedi, Christine Chiou, Bobeck Modjtahedi, David G. Telander, Lawrence S Morse, Susanna Soon Chun Park

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

■ BACKGROUND AND OBJECTIVE: To compare macular thickness measurements and segmentation error rates between Stratus optical coherence tomography (OCT) (Carl Zeiss Meditec, Inc., Dublin, CA), and Fourier-domain OCT (RTVue, Optovue, Inc., Fremont, CA). ■ PATIENTS AND METHODS: A retrospective study was performed of 93 normal and pathologic eyes from 79 subjects imaged with both OCT instruments on the same day. Both the macular thickness measurement for each Early Treatment Diabetic Retinopathy Study (ETDRS) zone and the incidence of segmentation error in the central macula between the two instruments were compared. ■ RESULTS: Macular thickness measurements for all nine ETDRS zones were higher with RTVue compared with Stratus OCT (P < .01). Linear regression analysis showed the highest correlation in the central macula (R 2 = 0.88), with progressively lower correlation peripherally. The overall segmentation error rate was 29% with Stratus OCT versus 32% with RTVue (P > .05). ■ CONCLUSION: Macular thickness measurement was greater with RTVue than with Stratus OCT in all ETDRS areas, with the best correlation seen in the central macula. No difference in segmentation error rate was noted between the two instruments.

Original languageEnglish (US)
Pages (from-to)301-310
Number of pages10
JournalOphthalmic Surgery Lasers and Imaging
Volume41
Issue number3
DOIs
StatePublished - May 2010

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Optical Coherence Tomography
Diabetic Retinopathy
Cohort Studies
Therapeutics
Retrospective Studies

ASJC Scopus subject areas

  • Ophthalmology
  • Surgery

Cite this

Comparison of macular thickness measurement and segmentation error rate between stratus and fourier-domain optical coherence tomography. / Modjtahedi, Sara; Chiou, Christine; Modjtahedi, Bobeck; Telander, David G.; Morse, Lawrence S; Park, Susanna Soon Chun.

In: Ophthalmic Surgery Lasers and Imaging, Vol. 41, No. 3, 05.2010, p. 301-310.

Research output: Contribution to journalArticle

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