Comparison of classical and autogenous systems of regulation in inducible operons

Michael A. Savageau

doi:10.1038/252546a0

Comparison of classical and autogenous systems of regulation in inducible operons

Michael A. Savageau

Research output: Contribution to journal › Article

164 Scopus citations

Abstract

The mechanism of autogenous regulation, whereby a protein directly controls the expression of its own structural gene, is compared on the basis of function with the classical mechanism, in which the structural gene of the regulator is itself unregulated. The autogenous mechanism is superior to the classical one in inducible catabolic systems governed by a repressor; the opposite is true if the regulator is an activator.

Original language	English (US)
Pages (from-to)	546-549
Number of pages	4
Journal	Nature
Volume	252
Issue number	5484
DOIs	https://doi.org/10.1038/252546a0
State	Published - 1974
Externally published	Yes

ASJC Scopus subject areas

General

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10.1038/252546a0

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